Tempus AI, Inc. vs Guardant Health Inc. - IPR2025-01434

Patent Owner's Mandatory Notices

Patent Owner's Power of Attorney

U.S. Patent No. 11,149,306 (Corrected)

Prosecution history for the ’306 patent (Corrected)

Declaration of Michael Metzker, Ph.D. (Corrected)

Curriculum Vitae of Michael Metzker, Ph.D. (Corrected)

PCT Publication No. WO 2013/123442 A1 (Corrected)

PCT Publication No. WO 2012/142213 A2 (Corrected)

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U.S. Patent Publication No. 2014/0296081 (Corrected)

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Guardant Health, Inc. v. Foundation Medicine, IPR2017- 01448, Paper 2 – Petition for Inter Partes Review of U.S. Patent No. 9,340,830 (Corrected)

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Guardant Health, Inc. v. University of Washington, IPR2022- 00816, Paper 3 – Petition for Inter Partes Review of U.S. Patent No. 10,760,127 (Corrected)

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Guardant Health, Inc. v. University of Washington, IPR2022- 01388, Paper 2 – Petition for Inter Partes Review of U.S. Patent No. 10,689,699 (Corrected)

Declaration of Sylvia D. Hall-Ellis, Ph.D (Corrected)

Guardant Health, Inc. v. University of Washington, IPR2022- 00935, Paper 2 – Petition for Inter Partes Review of U.S. Patent No. 10,287,631 (Corrected)

U.S. Provisional Patent Application No. 61/600535 (Corrected)

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Twinstrand Biosciences, Inc. v. Guardant Health, Inc., IPR2022-01400, Paper 41 – Final Written Decision (Corrected)

Twinstrand Biosciences, Inc. v. Guardant Health, Inc., IPR2022-01400, Paper 9 – Institution Decision (Corrected)

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International Human Genome Sequencing Consortium, Finishing the euchromatic sequence of the human genome, NATURE 431:931–945 (2004) (Corrected)

Forbes, et al., COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer, NUCLEIC ACIDS RESEARCH 39:D945–D950 (2011) (Corrected)

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Kircher et al., Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform, NUCLEIC ACIDS RESEARCH 40:e3 pp. 1–8 (2012) (Corrected)

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Schmitt et al., Detection of ultra-rare mutations by nextgeneration sequencing, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES 109: 14508- 14513 (2012) (Corrected)

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Cock et al., The Sanger FASTQ file format for sequences with quality scores, and the Solexa/Illumina FASTQ variants (Corrected)

CASAVA 1.8: enhanced variant calling in whole-genome resequencing data (2011) (Corrected)

Li et al., Mapping short DNA sequencing reads and calling variants using mapping quality scores, Genome Research 18:1851–1858 (2008) (Corrected)

Li & Durbin, Fast and accurate short read alignment with Burrows–Wheeler transform, Bioinformatics 25:1754–1760 (2009) (Corrected)

Li & Durbin, Fast and accurate long-read alignment with Burrows–Wheeler transform, Bioinformatics 26: 589–595 (2010) (Corrected)

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DePristo et al., A framework for variation discovery and genotyping using next-generation DNA sequencing data, NATURE GENETICS 43:491–498 (2011) and Online Methods (Corrected)

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Koboldt et al., VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing, GENOME RESEARCH 22:568–576 (2012) (Corrected)

Cibulskis et al., Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples, NATURE BIOTECHNOLOGY 31:213–219 (2013) (Corrected)

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Schatz et al., Assembly of large genomes using secondgeneration sequencing, GENOME RESEARCH 20:1165–1173 (2010) (Corrected)

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Notice: Notice filing date accorded

Updated Mandatory Notice

Updated Power of Attorney

Notice: Tempus Power of Attorney

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Ex. 1003 - Declaration of Michael L. Metzker, Ph.D.

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Petition: as filed