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Treatment Of Retinal Degeneration Using Gene Therapy - EP3110433

The patent EP3110433 was granted to The University OF Manchester on Feb 22, 2023. The application was originally filed on Feb 24, 2015 under application number EP15707722A. The patent is currently recorded with a legal status of "Patent Maintained As Amended".

EP3110433

THE UNIVERSITY OF MANCHESTER
Application Number
EP15707722A
Filing Date
Feb 24, 2015
Status
Patent Maintained As Amended
Jan 20, 2023
Publication Date
Feb 22, 2023
External Links
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Patent Summary

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Patent Oppositions (2)

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STRATAGEMApr 17, 2020STRATAGEM IPMWITHDRAWN
KELTIEApr 9, 2020CARPMAELS & RANSFORDWITHDRAWN

Patent Citations (6) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
OPPOSITIONUS2011224145
OPPOSITIONUS2013071373
OPPOSITIONWO2004009022
OPPOSITIONWO2006059081
OPPOSITIONWO2007131180
OPPOSITIONWO2010011404

Non-Patent Literature (NPL) Citations (19) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
INTERNATIONAL-SEARCH-REPORT- J. CEHAJIC-KAPETANOVIC ET AL, "Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2", MOLECULAR VISION, 17, (20110630), pages 1771 - 1783, XP055183839 [Y] 1-41 * abstract *
INTERNATIONAL-SEARCH-REPORT- Haoyu Mao ET AL, "Gene Delivery of Wild-Type Rhodopsin Rescues Retinal Function in an Autosomal Dominant Retinitis Pigmentosa Mouse Model", Therapeutic Targets of the TNF Superfamily, New York, NY, Springer New York, (20111111), vol. 723, pages 199 - 205, doi:10.1007/978-1-4614-0631-0_27, ISSN 0065-2598, ISBN 978-0-38-789520-8, XP055183733 [I] 42-81 * abstract * [Y] 1-41
INTERNATIONAL-SEARCH-REPORT- DENIZ DALKARA ET AL, "Inner Limiting Membrane Barriers to AAV-mediated Retinal Transduction From the Vitreous", MOLECULAR THERAPY, (20091211), vol. 17, no. 12, doi:10.1038/mt.2009.181, ISSN 1525-0016, pages 2096 - 2102, XP055183686 [X] 1-6,22-26 * abstract * [Y] 7-21,27-41
INTERNATIONAL-SEARCH-REPORT- ARPAD PALFI ET AL, "Adeno-Associated Virus-Mediated Rhodopsin Replacement Provides Therapeutic Benefit in Mice with a Targeted Disruption of the Rhodopsin Gene", HUMAN GENE THERAPY, (20100301), vol. 21, no. 3, doi:10.1089/hum.2009.119, ISSN 1043-0342, pages 311 - 323, XP055183897 [X] 42-81 * abstract *
OPPOSITION- Anonymous, "Opsin Classification", Wikipedia, (20140224), pages 1 - 6, XP055743252
OPPOSITION- CEHAJIC-KAPETANOVIC et al., "Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2", Mol. Vis., (20110630), vol. 17, pages 1771 - 1783, XP055183839
OPPOSITION- Haoyu Mao et al, "Therapeutic Targets of the TNF S Gene Delivery of Wild-Type Rhodopsin Rescues Retinal Function in an Autosomal Dominant Retinitis Pigmentosa Mouse Model", Adv Exp Med Biol., (20111111), vol. 723, pages 199 - 205, XP055183733
OPPOSITION- SCHON, C. et al., "Retinal gene delivery by adeno-associated virus (AAV) vectors: strategies and applications", Eur. J. Pharm Biopharm., vol. 95, doi:10.1016/j.ejpb.2015.01.009, (20150000), pages 343 - 352, (20150120), XP055533708
OPPOSITION- BI Arding et al., "Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration", Neuron, (20060406), vol. 50, no. 1, pages 23 - 33, XP002406402
OPPOSITION- CEHAJIC-KAPETANOVIC et al., "Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice", Mol. Ther.: Methods & Clin. Dev., (20180600), vol. 9, pages 192 - 202, XP055716131
OPPOSITION- CEHAJIC-KAPETANOVIC et al., "Enhancement of light sensitivity in retinal degeneration in mice by use of novel optogenetic approaches", The Lancet, (20140226), vol. 383, no. 1, page s33, XP055183695
OPPOSITION- CEHAJIC-KAPETANOVIC, J et al., "Enhancement of light sensitivity in retinal degeneration in mice by use of novel optogenetic approaches", Lancet, vol. 383, no. S33, doi:10.1016/S0140-6736(14)60296-8, (20140226), (20140226), XP055183695
OPPOSITION- DENIZ DALKARA et al., "Inner Limiting Membrane Barriers to AAV-mediated Retinal Transduction From the Vitreous", Mol. Ther., (20091211), vol. 17, no. 12, pages 2096 - 2102, XP055183686
OPPOSITION- DOROUDCHI et al., "Virally delivered Channelrhodopsin-2 Safely and Effectively Restores Visual Function in Multiple Mouse Models of Blindness", Mol. Ther., (20110419), vol. 19, no. 7, pages 1220 - 1229, XP008145711
OPPOSITION- LAGALI et al., "Light-activated channels targeted to ON bipolar cells restore visual function inretinal", Nature Neur., (20080427), vol. 11, no. 6, pages 667 - 675, XP003031411
OPPOSITION- LIN, B et al., "Restoration of visual function in retinal degeneration mice by ectopic expression of melanopsin", PNAS, vol. 105, no. 41, doi:10.1073/pnas.0806114105, (20081014), pages 16009 - 16014, (20081014), XP055353671
OPPOSITION- ARPAD PALFI et al., "Adeno-Associated Virus-Mediated Rhodopsin Replacement Provides Therapeutic Benefit in Mice with a Targeted Disruption of the Rhodopsin Gene", Human Gene Therapy, vol. 21, no. 3, ISSN 1043-0342, (20100301), pages 311 - 323, (20100222), XP055183897
OPPOSITION- ARPAD PALFI et al., "Adeno-Associated Virus-Mediated Rhodopsin ReplacementProvides Therapeutic Benefit in Mice with a Targeted Disruption of the Rhodopsin Gene", Hum. Gen. Ther., (20100301), vol. 21, no. 3, pages 311 - 323, XP055183897
OPPOSITION- YIN, L et al., "Intravitreal injection of AAV2 transduces macaque inner retina", Invest Ophthalmol Vis Sci., vol. 52, no. 5, doi:10.1167/iovs.10-6250, (20110425), pages 2775 - 83, (20110425), XP002714132

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