| EXAMINATION | - BLAUVELT ANDREW ET AL, "No Increased Risk of Overall Infection in Adults with Moderate-to-Severe Atopic Dermatitis Treated for up to 4 Years with Dupilumab", ADVANCES IN THERAPY., US, vol. 40, no. 1, doi:10.1007/s12325-022-02322-y, ISSN 0741-238X, (20221101), pages 367 - 380, URL: https://link.springer.com/article/10.1007/s12325-022-02322-y/fulltext.html, XP093104397 |
| OPPOSITION | - A Garriga, "71st ANNUAL MEETING OF THE AMERICAN ACADEMY OF DERMATOLOGY (AAD)", Drugs of the Future, (20130301), pages 275 - 279, XP055566346 |
| OPPOSITION | - Anonymous, "CIBINQO (abrocitinib) tablets, for oral use - HIGHLIGHTS OF PRESCRIBING INFORMATION", FDA, (20230201), XP093283555 |
| OPPOSITION | - Anonymous, "Dupilumab - ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS", EMEA, (20220901), XP093231635 |
| OPPOSITION | - Anonymous, "International Nonproprietary Names for Pharmaceutical Substances (INN), List 108", WHO Drug Information, (20120101), vol. 26, no. 4, pages 401 - 471, XP055932074 |
| OPPOSITION | - Anonymous, "Ringworm and Fungal Nail Infections Basics", U.S. CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC), (20240424), U.S. CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC), URL: https://www.cdc.gov/ringworm/about/index.html#print, XP093238349 |
| OPPOSITION | - Bieber Thomas R.M., Thaci Diamant, Graham Neil, Pirozzi Gianluca, Teper Ariel, Ren Haobo, Radin Allen, "Dupilumab Monotherapy in Adults with Moderate-to-Severe Atopic Dermatitis: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study", J Allergy Clin Immunol.; AB404 Abstracts, (20140201), XP093238339 |
| OPPOSITION | - Boguniewicz, M. ; Leung, D.Y.M., "Recent insights into atopic dermatitis and implications for management of infectious complications", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20100101), vol. 125, no. 1, ISSN 0091-6749, pages 4 - 13, XP026823290 |
| OPPOSITION | - Charles Bankhead, "IL-4 Antibody Tames Atopic Dermatitis", Medpage Today, (20130303), pages 1 - 3, Medpage Today, URL: https://www.medpagetodaY.com/meetingcoverage/aad/37636, (20190308), XP055566311 |
| OPPOSITION | - D10 - Abstracts of “6th International Investigative Dermatology Meeting” May 8 11, 2013 in Edinburgh, Scotland, United Kingdom, J Invest Dermatol. 2013 May;133 Suppl 1:S1-311 |
| OPPOSITION | - D13a - PRINTOUT OF THE WEBSITE OF SCIENCEDIRECT SHOWING THAT D13 WAS AVAILABLE ONLINE AS OF JANUARY 23, 2014 |
| OPPOSITION | - D13b - orrespondence with the Editors of The Journal of Allergy and Clinical Immunology about publication date of D13 |
| OPPOSITION | - D1 - APPLICANTS’ SUBMISSION FILED DURING EXAMINATION PROCEEDINGS ON AUGUST 8, 2019 |
| OPPOSITION | - D36 - Beck et al (Supplementary Appendix) |
| OPPOSITION | - D37 - Beck et al (Protocol) |
| OPPOSITION | - D47 - Infection v. Colonization. Multi Drug Resistant Organisms Management in Long Term Care Facilities Workshop Louisiana Office of Public Health Healthcare Associated Infections Program. https://ldh.la.gov/assets/oph/Center-PHCH/Center- CH/infectiousepi/HAI/MDRO2017/handouts/ColonizationvInfection.pdf - 2017; no date to be found on the slides |
| OPPOSITION | - D49 - Thaçi et al (Supplementary Appendix) |
| OPPOSITION | - D50 - CDR Clinical Review Report for Dupixent (Appendix 4). CADTH COMMON DRUG REVIEW, 117-127. June 2020 |
| OPPOSITION | - D66 - Regeneron Pharmaceuticals, Inc., SEC Form 8-K dated March 4, 2024, including Exhibit 99.1: Bieber T. et al. Dupilumab Monotherapy in Adults with Moderate-to-Severe Atopic Dermatitis:A 12-Week, Randomized, Double-Blind, Placebo Controlled Study ("Bieber et al.") |
| OPPOSITION | - D71 - 2014 AAAI program for late breaking abstracts WayBack Machine print out |
| OPPOSITION | - D73 - JACI List of Issues Archive |
| OPPOSITION | - D81 - Use of Dupilumab for Disseminated Fungal Infection (date?) |
| OPPOSITION | - D9 - Copy of four posters (#1042, #1048, #1049, #1050) presented by Regeneron Pharmaceuticals, Inc. and Sanofi among others at the “6th International Investigative Dermatology Meeting” in Edinburgh, Scotland, United Kingdom, May 8-11, 2013 |
| OPPOSITION | - Ference, Last, "Choosing Topical Corticosteroids", AMERICAN FAMILY PHYSICIAN, American Academy of Family Physicians, US, US , (20090101), vol. 79, no. 2, ISSN 0002-838X, pages 135 - 140, XP093283581 |
| OPPOSITION | - Mark G Lebwohl, James Q. Del Rosso, William Abramovits, Brian Berman, David E. Cohen, Emma Guttman-Yassky, Anthony J. Mancini, And Lawrence A. Schachner, "Pathways to Managing Atopic Dermatitis: Consensus From the Experts", JOURNAL OF DRUGS IN DERMATOLOGY, STRATEGIC COMMUNICATION IN DERMATOLOGY, NEW YORK, NY, US, US , (20130601), vol. 6, no. 7 Suppl, ISSN 1545-9616, pages S2 - S18, XP055436108 |
| OPPOSITION | - Milo Gibaldi, "Chapter 1: Introduction to Pharmacokinetics", Milo Gibaldi, MILO GIBALDI, Biopharmaceutics and Clinical Pharmacokinetics, FOURTH EDITION, Lea & Febinger, (19900101), pages 1 - 13, ISBN 0-8121-1346-2, XP009558949 |
| OPPOSITION | - Paris, Tarrytown, "SANOFI AND REGENERON ANNOUNCE PUBLICATION OF POSITIVE PHASE 2A RESULTS OF DUPILUMAB IN ASTHMA IN THE NEW ENGLAND JOURNAL OF MEDICINE", New England Journal of Medicine, (20130521), pages 1 - 3, XP055928700 |
| OPPOSITION | - Rehmus Wingfield E., "Cellulitis", MSD MANUAL - PROFESSIONAL VERSION, (20230601), MSD MANUAL - PROFESSIONAL VERSION, URL: https://www.msdmanuals.com/professional/dermatologic-disorders/bacterial-skin-infections/cellulitis, XP093238351 |
| OPPOSITION | - "Sanofi and Regeneron Report Positive Proof-of-Concept Data for Dupilumab, an IL-4R alpha Antibody, in Atopic Dermatitis", 71st Annual Meeting of the American Academy of Dermatology, (20130302), pages 1 - 3, XP007922251 |
| OPPOSITION | - Stuart Proudfoot, "19. Dosage regimens", Pharmaceuticals: The Science of Dosage Form Administratio. 2nd Ed, (20020101), pages 275 - 288, XP055397036 |
| OPPOSITION | - Thomas L. Bosshardt, Vernon J. Henderson, Claude H. Organ Jr., "Necrotizing soft-tissue infections", Thomas L. Bosshardt, Vernon J. Henderson, Claude H. Organ Jr., Rene G. Holzheimer, John A. Mannick, Surgical Treatment - Evidence-Based and Problem-Oriented, W. Zuckschwerdt Verlag, (20010101), pages 656 - 660, ISBN 3-88603-714-2, XP009558948 |
| OPPOSITION | - Cohen Yehuda Z., Zhang Xiaojia, Xia Binfeng, Kosloski Matthew P., Kamal Mohamed A., Davis John D., Kanamaluru Vanaja, Xu Christine, "Pharmacokinetics of Subcutaneous Dupilumab Injection With an Autoinjector Device or Prefilled Syringe", Clinical Pharmacology in Drug Development, Wiley-Blackwell Publishing Ltd., GB, GB , (20220501), vol. 11, no. 5, doi:10.1002/cpdd.1073, ISSN 2160-763X, pages 675 - 681, XP093235860 |
| OPPOSITION | - Lin Y T, Wang C T, Chiang B L, "Role of bacterial pathogens in atopic dermatitis.", CLINICAL REVIEWS IN ALLERGY AND IMMUNOLOGY, HUMANA PRESS, TOTOWA, NJ, US, US , (20071201), vol. 33, no. 3, doi:10.1007/s12016-007-0044-5, ISSN 1080-0549, pages 167 - 177, XP002739302 |
| OPPOSITION | - Silverberg Jonathan I., Silverberg Nanette B., "Atopic Dermatitis: Update on Pathogenesis and Comorbidities", Current Dermatology Reports, (20121201), vol. 1, no. 4, doi:10.1007/s13671-012-0021-y, pages 168 - 178, XP093054447 |
| OPPOSITION | - Nilsson, E.J. ; Henning, C.G. ; Magnusson, J., "Topical corticosteroids and Staphylococcus aureus in atopic dermatitis", Journal of the American Academy of Dermatology, Mosby, Inc, US, US , (19920701), vol. 27, no. 1, doi:10.1016/0190-9622(92)70151-5, ISSN 0190-9622, pages 29 - 34, XP025613504 |
| OPPOSITION | - Theo Rispens, Gestur Vidarsson, "Chapter 9 - Human IgG Subclasses", Antibody Fc: Linking Adaptive and Innate Immunity, Academic Press, (20140101), pages 159 - 177, doi:10.1016/B978-0-12-394802-1.00009-1, ISBN 9780123948021, XP009558950 |
| OPPOSITION | - Werfel Thomas, Kapp Alexander, "Atopic dermatitis and allergic contact dermatitis", Allergy, Elsevier , (20120101), pages 263 - 286, doi:10.1016/C2009-0-46113-0, ISBN 978-0-7234-3658-4, XP093235762 |
| OPPOSITION | - Giavina-Bianchi Mara, Rizzo Luiz Vicente, Giavina-Bianchi Pedro, "Severe atopic dermatitis: Dupilumab is not just safer, but more efficient", ALLERGOLOGIA ET IMMUNOPATHOLOGIA, GARSI, MADRID,, ES, ES , (20201101), vol. 48, no. 6, doi:10.1016/j.aller.2019.12.005, ISSN 0301-0546, pages 792 - 797, XP093283570 |
| OPPOSITION | - Howell, M.D. Boguniewicz, M. Pastore, S. Novak, N. Bieber, T. Girolomoni, G. Leung, D.Y.M., "Mechanism of HBD-3 deficiency in atopic dermatitis", CLINICAL IMMUNOLOGY, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20061115), vol. 121, no. 3, doi:10.1016/j.clim.2006.08.008, ISSN 1521-6616, pages 332 - 338, XP005740934 |
| OPPOSITION | - Ong Peck Y., Leung Donald Y.M., "The Infectious Aspects of Atopic Dermatitis", IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA, SAUNDERS, PHILADELPHIA, US, US , (20100801), vol. 30, no. 3, doi:10.1016/j.iac.2010.05.001, ISSN 0889-8561, pages 309 - 321, XP093238355 |
| OPPOSITION | - Spergel J, "Atopic dermatitis and the atopic march", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20031201), vol. 112, no. 6, doi:10.1016/j.jaci.2003.09.033, ISSN 0091-6749, pages S118 - S127, XP093238364 |
| OPPOSITION | - for the European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Group Akdis, C.A. Akdis, M. Bieber, T. Bindslev-Jensen, C. Boguniewicz, M. Eigenmann, P. Hamid, Q. Kapp, A. Leung, D.Y.M. Lipozencic, J. Lug, "Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20060701), vol. 118, no. 1, doi:10.1016/j.jaci.2006.03.045, ISSN 0091-6749, pages 152 - 169, XP005523634 |
| OPPOSITION | - Boguniewicz, M. Schmid-Grendelmeier, P. Leung, D.Y.M., "Atopic dermatitis", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20060701), vol. 118, no. 1, doi:10.1016/j.jaci.2006.04.044, ISSN 0091-6749, pages 40 - 43, XP005523619 |
| OPPOSITION | - Jensen, J.M. ; Pfeiffer, S. ; Witt, M. ; Brautigam, M. ; Neumann, C. ; Weichenthal, M. ; Schwarz, T. ; Folster-Holst, R. ; Proksch, E., "Different effects of pimecrolimus and betamethasone on the skin barrier in patients with atopic dermatitis", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20090501), vol. 123, no. 5, doi:10.1016/j.jaci.2009.03.032, ISSN 0091-6749, pages 1124 - 1133, XP026083375 |
| OPPOSITION | - Emma Guttman-Yassky; Kristine E. Nograles; James G. Krueger;, "Contrasting pathogenesis of atopic dermatitis and psoriasisPart I: Clinical and pathologic concepts", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20110105), vol. 127, no. 5, doi:10.1016/j.jaci.2011.01.053, ISSN 0091-6749, pages 1110 - 1118, XP028198096 |
| OPPOSITION | - Alexander A. Navarini; Lars E. French; Gnther F.L. Hofbauer;, "Interrupting IL-6receptor signaling improves atopic dermatitis but associates with bacterial superinfection", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , vol. 128, no. 5, doi:10.1016/j.jaci.2011.09.009, ISSN 0091-6749, pages 1128 - 1130, XP028330236 |
| OPPOSITION | - Tkachenko Eugene; Rawson Renee; La Elizabeth; Doherty Taylor A.; Baum Rachel; Cavagnero Kellen; Miyanohara Atsushi; Dohil Ranjan; Kurten Richard C.; Aceves Seema S., "Rigid substrate induces esophageal smooth muscle hypertrophy and eosinophilic esophagitis fibrotic gene expression", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20151102), vol. 137, no. 4, doi:10.1016/j.jaci.2015.09.020, ISSN 0091-6749, page 1270, XP029494556 |
| OPPOSITION | - He Helen; Del Duca Ester; Diaz Aisleen; Kim Hyun Je; Gay-Mimbrera Jesús; Zhang Ning; Wu Jianni; Beaziz Jessica; Estrada Yeriel; Krueger James G.; Pavel Ana B.; Ruano Juan; Guttman-Yassky Emma, "Mild atopic dermatitis lacks systemic inflammation and shows reduced nonlesional skin abnormalities", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20201001), vol. 147, no. 4, doi:10.1016/j.jaci.2020.08.041, ISSN 0091-6749, pages 1369 - 1380, XP086529008 |
| OPPOSITION | - Simpson Eric L., Schlievert Patrick M., Yoshida Takeshi, Lussier Stephanie, Boguniewicz Mark, Hata Tissa, Fuxench Zelma, De Benedetto Anna, Ong Peck Y., Ko Justin, Calatroni Agustin, Rudman Spergel Amanda K., Plaut Marshall, Quataert Sally A., Kilgore Samuel H., Peterson Liam, Gill Ann L., David Gloria, Mosmann Tim, Gill Steven R., Leung Donald Y.M., Beck Lisa A., "Rapid reduction in Staphylococcus aureus in atopic dermatitis subjects following dupilumab treatment", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20231101), vol. 152, no. 5, doi:10.1016/j.jaci.2023.05.026, ISSN 0091-6749, pages 1179 - 1195, XP093283563 |
| OPPOSITION | - Traidl Stephan; Harries Leonard; Kienlin Petra; Begemann Gabriele; Roesner Lennart M.; Werfel Thomas, "Dupilumab strengthens herpes simplex virus type 1-specific immune responses in atopic dermatitis", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20230901), vol. 152, no. 6, doi:10.1016/j.jaci.2023.08.024, ISSN 0091-6749, page 1460, XP087436552 |
| OPPOSITION | - Arkwright Peter D., Motala Cassim, Subramanian Hamsa, Spergel Jonathan, Schneider Lynda C., Wollenberg Andreas, "Management of Difficult-to-Treat Atopic Dermatitis", The journal of allergy and clinical immunology : an official journal of AAAAI, American Academy of Allergy Asthma & Immunology, Elsevier BV, NL, NL , (20130301), vol. 1, no. 2, doi:10.1016/j.jaip.2012.09.002, ISSN 2213-2198, pages 142 - 151, XP093283582 |
| OPPOSITION | - Furue Masutaka, Matsumoto Tsuyoshi, Yamamoto Tetsuo, Takeuchi Satoshi, Esaki Hitokazu, Chiba Takahito, Yamaguchi Hideyo, "Correlation between serum thymus and activation-regulated chemokine levels and stratum corneum barrier function in healthy individuals and patients with mild atopic dermatitis", Journal of Dermatological Science, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20120401), vol. 66, no. 1, doi:10.1016/j.jdermsci.2012.01.011, ISSN 0923-1811, pages 60 - 63, XP093238366 |
| OPPOSITION | - Thaçi Diamant; Simpson Eric L; Beck Lisa A; Bieber Thomas; Blauvelt Andrew; Papp Kim; Soong Weily; Worm Margitta; Szepietowski Jacek C; Sofen Howard; Kawashima Makoto; Wu Richard; Weinstein Steven P; Graham Neil M H; Pirozzi Gianluca; Teper Ariel; Sutherland E Rand; Mastey Vera; Stahl Neil; Yancopoulos George D; Ardeleanu Marius, "Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial", The Lancet, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20151008), vol. 387, no. 10013, doi:10.1016/S0140-6736(15)00388-8, ISSN 0140-6736, pages 40 - 52, XP029378549 |
| OPPOSITION | - Eisenstein M, "Something new under the skin", Nature Biotechnology, Nature Publishing Group US, New York, New York, (20110101), vol. 29, no. 2, doi:10.1038/nbt.1768, ISSN 1087-0156, pages 107 - 109, XP009152843 |
| OPPOSITION | - Pournaras Constance C., Jann Lübbe, Jean-Hilaire Surat, "Staphylococcal Colonization in Atopic Dermatitis Treatment with Topical Tacrolimus (Fk506) ", THE JOURNAL OF INVESTIGATIVE DERMATOLOGY, (20010301), vol. 116, no. 3, doi:10.1046/j.1523-1747.2001.12799.x, pages 480 - 481, XP093283580 |
| OPPOSITION | - Paintaud Gilles, "Pharmacocinétique des anticorps monoclonaux", M/S MEDECINE SCIENCES., SOCIETE DES PERIODIQUES FLAMMARION, PARIS,, FR, FR , (20091201), vol. 25, no. 12, doi:10.1051/medsci/200925121057, ISSN 0767-0974, pages 1057 - 1062, XP093238361 |
| OPPOSITION | - ONG P Y, ET AL., "ENDOGENOUS ANTIMICROBIAL PEPTIDES AND SKIN INFECTIONS IN ATOPIC DERMATITIS", The New England journal of medicine, Massachusetts Medical Society, US, US , (20021010), vol. 347, no. 15, doi:10.1056/NEJMoa021481, ISSN 0028-4793, pages 1151 - 1160, XP008028910 |
| OPPOSITION | - Beck Lisa A; Thaçi Diamant; Hamilton Jennifer D; Graham Neil M; Bieber Thomas; Rocklin Ross; Ming Jeffrey E; Ren Haobo; Kao Richard; Simpson Eric; Ardeleanu Marius; Weinstein Steven P; Pirozzi Gianluca; Guttman-Yassky Emma; Suárez-Fariñas Mayte; Hager Melissa D; Stahl Neil; Yancopoulos George D; Radin Allen R, "Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.", New England Journal of Medicine, The - NEJM, Massachusetts Medical Society, US, US , (20140710), vol. 371, no. 2, doi:10.1056/NEJMoa1314768, ISSN 1533-4406, pages 130 - 139, XP009180485 |
| OPPOSITION | - Thomas Bieber, "Atopic Dermatitis", The New England Journal of Medicine, (20080403), vol. 358, no. 14, doi:10.1056/NEJMra074081, pages 1483 - 1494, XP009194018 |
| OPPOSITION | - Remitz Anita, Kyllönen Hannele, Granlund Håkan, Reitamo Sakari, "Tacrolimus ointment reduces staphylococcal colonization of atopic dermatitis lesions", Journal of Allergy and Clinical Immunology, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20010101), vol. 107, no. 1, doi:10.1067/mai.2001.112131, ISSN 0091-6749, pages 196 - 197, XP093238360 |
| OPPOSITION | - Wollenberg Andreas, Wetzel Stefanie, Burgdorf Walter H C, Haas Jürgen, "Viral infections in atopic dermatitis: Pathogenic aspects and clinical management", J Allergy Clin Immunol, (20031001), vol. 112, no. 4, doi:10.1067/mai.2003.1775, pages 667 - 674, XP093238357 |
| OPPOSITION | - Hartmann Jan, Moitinho‐silva Lucas, Sander Nicole, Harder Inken, Häsler Robert, Rodriguez Elke, Haufe Eva, Kleinheinz Andreas, Abraham Susanne, Heratizadeh Annice, Weisshaar Elke, Schäkel Knut, Handrick Christiane, Augustin Matthias, Wollenberg Andreas, Staubach‐renz Petra, Ertner Konstantin, Sticherling Michael, Schwarz Beate, Quist Sven, Wiemers Franca, Schenck Florian, Wildberger Julia, Tittmann Lukas, Lieb Wolfgang, Schmitt Jochen, Werfel Thomas, Weidinger Stephan, "Dupilumab but not cyclosporine treatment shifts the microbiome toward a healthy skin flora in patients with moderate‐to‐severe atopic dermatitis", ALLERGY, Wiley-Blackwell Publishing Ltd., United Kingdom, United Kingdom , (20230801), vol. 78, no. 8, doi:10.1111/all.15742, ISSN 0105-4538, pages 2290 - 2300, XP093283567 |
| OPPOSITION | - Ring J., Alomar A., Bieber T., Deleuran M., Fink‐wagner A., Gelmetti C., Gieler U., Lipozencic J., Luger T., Oranje A.P., Schäfer T., Schwennesen T., Seidenari S., Simon D., Ständer S., Stingl G., Szalai S., Szepietowski J.C., Taïeb A., Werfel T., Wollenberg A., Darsow U., "Guidelines for treatment of atopic eczema (atopic dermatitis) Part I", JEADV , The Journal of the European Academy of Dermatology and Venereology, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM., NL, NL , (20120101), vol. 26, no. 8, doi:10.1111/j.1468-3083.2012.04635.x, ISSN 0926-9959, pages 1045 - 1060, XP093235834 |
| OPPOSITION | - Mark Boguniewicz, Et Al., "Atopic Dermatitis: A Disease of Altered Skin Barrier and Immune Dysregulation", Immunological Reviews, (20110731), vol. 242, no. 1, doi:10.1111/j.1600-065X.2011.01027.x, pages 233 - 246, XP055581377 |
| OPPOSITION | - Kei-ichi Yamanaka ; Hitoshi Mizutani, "The Role of Cytokines/Chemokines in the Pathogenesis of Atopic Dermatitis", Kei-ichi Yamanaka ; Hitoshi Mizutani, T. Shiohara, Pathogenesis and management of atopic dermatitis, Karger, (20110101), pages 80 - 92, doi:10.1159/000323299, ISBN 978-3-8055-9686-2, XP009558947 |
| OPPOSITION | - Ong Peck Y, "Editorial update on emerging treatments of atopic dermatitis", Expert opinion on emerging drugs England, Informa Healthcare, UK, UK , (20120601), vol. 17, no. 2, doi:10.1517/14728214.2012.668884, ISSN 1744-7623, pages 129 - 133, XP009171977 |
| OPPOSITION | - Petry V, Bessa G R, Poziomczyck C S, Oliveira C F, Weber M B, Bonamigo R R, d'Azevedo P A, "Bacterial skin colonization and infections in patients with atopic dermatitis.", ANAIS BRASILEIROS DE DERMATOLOGIA, ECN-ED. CIENTIFICA NACIONAL, RIO DE JANEIRO, BR, BR , (20120901), vol. 87, no. 5, doi:10.1590/S0365-05962012000500010, ISSN 0365-0596, pages 729 - 734, XP002739301 |
| OPPOSITION | - Chong Albert C, Visitsunthorn Kittipos, Ong Peck Y, "Genetic/Environmental Contributions and Immune Dysregulation in Children with Atopic Dermatitis", Journal of Asthma and Allergy, Dove Medical Press, Volume 15, doi:10.2147/JAA.S293900, ISSN 1178-6965, pages 1681 - 1700, XP093238365 |
| OPPOSITION | - Diane R. Mould, Bruce Green, "Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies", BIODRUGS, Adis International Ltd., NZ, NZ , (20100201), vol. 24, no. 1, doi:10.2165/11530560-000000000-00000, ISSN 1173-8804, pages 23 - 39, XP009514743 |
| OPPOSITION | - Bai Shuang; Jorga Karin; Xin Yan; Jin Denise; Zheng Yanan; Damico-Beyer Lisa A; Gupta Manish; Tang Meina; Allison David E; Lu Dan; Zhang Yi; Joshi Amita; Dresser Mark J, "A Guide to Rational Dosing of Monoclonal Antibodies", CLINICAL PHARMACOKINETICS., ADIS INTERNATIONAL LTD., AUCKLAND, NZ, NZ , (20120101), vol. 51, no. 2, doi:10.2165/11596370-000000000-00000, ISSN 0312-5963, pages 119 - 135, XP009184175 |
| OPPOSITION | - Donald Y.M. Leung, "New Insights into Atopic Dermatitis: Role of Skin Barrier and Immune Dysregulation", ALLERGOLOGY INTERNATIONAL, Japanese Society of Allergology, JP, JP , (20130101), vol. 62, no. 2, doi:10.2332/allergolint.13-RAI-0564, ISSN 1323-8930, pages 151 - 161, XP055520366 |
| OPPOSITION | - Biedermann T., "Dissecting the role of infections in atopic dermatitis", ACTA DERMATO-VENEREOLOGICA., Taylor & Francis Ltd., United Kingdom, United Kingdom , vol. 86, no. 2, doi:10.2340/00015555-0047, ISSN 0001-5555, pages 99 - 109, XP093238332 |
| OPPOSITION | - Ogonowska Patrycja, Gilaberte Yolanda, Barańska-Rybak Wioletta, Nakonieczna Joanna, "Colonization With Staphylococcus aureus in Atopic Dermatitis Patients: Attempts to Reveal the Unknown", Frontiers in Microbiology, Frontiers Media, Lausanne, Lausanne , vol. 11, doi:10.3389/fmicb.2020.567090, ISSN 1664-302X, XP093238363 |
| OPPOSITION | - Umemoto Naoka, Kakurai Maki, Matsumoto Takanao, Mizuno Kenta, Cho Otomi, Sugita Takashi, Demitsu Toshio, "Dupilumab Alters Both the Bacterial and Fungal Skin Microbiomes of Patients with Atopic Dermatitis", Microorganisms, MDPI AG, Switzerland, Switzerland, vol. 12, no. 1, doi:10.3390/microorganisms12010224, ISSN 2076-2607, page 224, XP093283576 |
| OPPOSITION | - Olesen Caroline Meyer, Ingham Anna Cäcilia, Thomsen Simon Francis, Clausen Maja-Lisa, Andersen Paal Skytt, Edslev Sofie Marie, Yüksel Yasemin Topal, Guttman-Yassky Emma, Agner Tove, "Changes in Skin and Nasal Microbiome and Staphylococcal Species Following Treatment of Atopic Dermatitis with Dupilumab", Microorganisms, MDPI AG, Switzerland, Switzerland, vol. 9, no. 7, doi:10.3390/microorganisms9071487, ISSN 2076-2607, page 1487, XP093283572 |
| OPPOSITION | - Bury Jordan, Zirwas Matthew, "Unexpected Clinical Lessons Learned From IL-4 and IL-13 Blockade", JOURNAL OF DRUGS IN DERMATOLOGY, STRATEGIC COMMUNICATION IN DERMATOLOGY, NEW YORK, NY, US, US , (20231001), vol. 22, no. 10, doi:10.36849/JDD.7249, ISSN 1545-9616, pages 1007 - 1008, XP093283561 |
| OPPOSITION | - Eric B. Brandt, "Th2 Cytokines and Atopic Dermatitis", Journal of Clinical & Cellular Immunology, (20110101), vol. 02, no. 03, doi:10.4172/2155-9899.1000110, pages 1 - 13, XP055386816 |
| OPPOSITION | - Bieber Thomas, "Atopic Dermatitis", ANNALS OF DERMATOLOGY, KOREAN DERMATOLOGICAL ASSOCIATION, SEOUL, KR, KR , (20100101), vol. 22, no. 2, doi:10.5021/ad.2010.22.2.125, ISSN 1013-9087, page 125, XP093238354 |
