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Methods Of Monitoring Immunosuppressive Therapies In A Transplant Recipient - EP3117012

The patent EP3117012 was granted to Caredx on Feb 20, 2019. The application was originally filed on Mar 13, 2015 under application number EP15761889A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3117012

CAREDX
Application Number
EP15761889A
Filing Date
Mar 13, 2015
Status
Granted And Under Opposition
Jan 18, 2019
Grant Date
Feb 20, 2019
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (2)

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J A KEMPNov 20, 2019J A KEMPADMISSIBLE
REGIMBEAUNov 20, 2019REGIMBEAUADMISSIBLE

Patent Citations (14) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
INTERNATIONAL-SEARCH-REPORTUS2012295810
INTERNATIONAL-SEARCH-REPORTUSRE39920E
INTERNATIONAL-SEARCH-REPORTWO2010009398
INTERNATIONAL-SEARCH-REPORTWO2013049892
INTERNATIONAL-SEARCH-REPORTWO2014194113
OPPOSITIONUS2012295810
OPPOSITIONUS2013024127
OPPOSITIONWO2011057061
OPPOSITIONWO2012019200
OPPOSITIONWO2013043922
OPPOSITIONWO2013049892
OPPOSITIONWO2013159035
OPPOSITIONWO2014194113
SEARCHWO2013043922

Non-Patent Literature (NPL) Citations (16) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
INTERNATIONAL-SEARCH-REPORT- SNYDER, TM et al., "Universal Noninvasive Detection Of Solid Organ Transplant Rejection.", Proc Natl Acad Sci USA., (20110412), vol. 108, no. 15, pages 6229 - 62 34, XP055129832 [X] 1-9 * ; abstract; page 6232, first column, second paragraph to second column, second paragraph; page 6233, first column, second paragraph to second column, first paragraph; page 6234, first column, second to fourth paragraphs; figure 4; DOI: 10.1073/pnas.1013924108. *
OPPOSITION- PAKSTIS AJ et al., "SNPs for a universal individual identification panel", Hum Gent., (20091100), vol. 127, no. 3, pages 315 - 24 24, XP019781746-
OPPOSITION- JUN G et al., "Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data", Am J Hum Genet., (20120000), vol. 91, no. 5, doi:10.1016/j.ajhg.2012.09.004, pages 839 - 848, XP055442346
OPPOSITION- CRESPO-LEIRO MG et al., "Utility of Gene Expression Profiling test (GEP) score instability to predict future clinical outcomes in heart transplant: results from the CARGO 2 European -based multicentre trial", J Heart Lung Transpl., (20130400), vol. 32, no. 4, doi:10.1016/j.healun.2013.01.238, pages 1136 - 4, XP055392424
OPPOSITION- FRAZER KA, BALLINGER DG et al., "A second generation human haplotype map of over 3.1 million SNPs. Nature", International HapMap Consortium, (20071000), vol. 449, no. 7164, pages 851 - 861, XP055654237
OPPOSITION- NIELSEN R et al., "Genotype and SNP calling from next-generation sequencing data", Nat Rev Genet., (20110000), vol. 12, no. 6, doi:10.1038/nrg2986, pages 443 - 451, XP055046801
OPPOSITION- SNYDER et al., "Universal noninvasive detection of solid organ transplant rejection - supporting information", PNAS, (20110328), vol. 108, no. 15, pages 6229 - 6234, XP055524568
OPPOSITION- SNYDER TM et al., "Universal noninvasive detection of solid organ transplant rejection", Proc Natl Acad Sci., (20110328), vol. 108, no. 15, doi:10.1073/pnas.1013924108, pages 6229 - 6234, XP055524568
OPPOSITION- DE VLAMINCK I et al., "Circulating Belongs to cell -free DNA enables noninvasive diagnosis of heart the prior transplant rejection", Sci Transpl Med., (20140618), vol. 6, no. 241, page 24tra77, XP008177554
OPPOSITION- MACHER HC et al., "Monitoring of transplanted liver health by quantification the prior of organ-specific genomic marker in circulating DNA from art under receptor", PLoS One, (20141209), vol. 9, no. 12, page e113987, XP055654230
OPPOSITION- BECK et al., "Digital Droplet PCR for Rapid Quantification of Donor DNA in the Circulation of Transplant Recipients as a Potential Universal Biomarker of Graft Injury", Clinical Chemistry, (20130112), vol. 59, no. 12, pages 1732 - 1741, XP055392164
OPPOSITION- BECK J et al., "Digital droplet PCR for rapide quantification of donor DNA in the circulation of transplant recipients as a potential universal biomarker of graft injury", Clin Chem., (20131201), vol. 59, no. 12, pages 1732 - 1741, XP055392164
SEARCH- ANDREW J PAKSTIS ET AL, "SNPs for a universal individual identification panel", HUMAN GENETICS, SPRINGER, BERLIN, DE, (20091124), vol. 127, no. 3, ISSN 1432-1203, pages 315 - 324, XP019781746 [Y] 1-17 * the whole document * * Table 1 *-
SEARCH- M.G. CRESPO-LEIRO ET AL, "Utility of Gene Expression Profiling Test (GEP) Score Instability To Predict Future Clinical Outcomes in Heart Transplant: Results from the CARGO 2 European-Based Multicenter Trial", JOURNAL OF HEART AND LUNG TRANSPLANTATION, US, (20130401), vol. 32, no. 4, doi:10.1016/j.healun.2013.01.238, ISSN 1053-2498, pages S113 - S114, XP055392424 [Y] 1-17 * the whole document *
SEARCH- DE VLAMINCK IWIJN ET AL, "Circulating cell-free DNA enables noninvasive diagnosis of heart transplant rejection", SCIENCE TRANSLATIONAL MEDI, vol. 6, no. 241, doi:10.1126/SCITRANSLMED.3007803, ISSN 1946-6242, (20140618), page 241ra77, (20140618), XP008177554 [XP] 1,4,8,9,11,12,14 * the whole document * * Fig. 1 * [Y] 2,3,5-7,10,13,15-17
SEARCH- J. BECK ET AL, "Digital Droplet PCR for Rapid Quantification of Donor DNA in the Circulation of Transplant Recipients as a Potential Universal Biomarker of Graft Injury", CLINICAL CHEMISTRY., WASHINGTON, DC., (20131201), vol. 59, no. 12, doi:10.1373/clinchem.2013.210328, ISSN 0009-9147, pages 1732 - 1741, XP055392164 [X] 1,4,8,9,11,12,14 * the whole document * * p. 1732-1733; p. 1741, col. 1 * [Y] 2,3,5-7,10,13,15-17

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