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Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells - EP3178483

The patent EP3178483 was granted to The University OF Tokyo on Apr 29, 2020. The application was originally filed on Jun 3, 2011 under application number EP16188203A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3178483

THE UNIVERSITY OF TOKYO
Application Number
EP16188203A
Filing Date
Jun 3, 2011
Status
Granted And Under Opposition
Mar 27, 2020
Grant Date
Apr 29, 2020
External Links
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GRUNDJan 29, 2021GRUNDADMISSIBLE
NESTLEJan 29, 2021ELKINGTON AND FIFEADMISSIBLE
POTTER CLARKSONJan 29, 2021POTTER CLARKSONADMISSIBLE
STRAWMANJan 29, 2021BRAND MURRAY FULLERWITHDRAWN

Patent Citations (15) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS6368586
OPPOSITIONAU2001276160B
OPPOSITIONDE102006062250
OPPOSITIONEP1749538
OPPOSITIONEP1955706
OPPOSITIONEP2575835
OPPOSITIONJP2009084215
OPPOSITIONWO2004085628
OPPOSITIONWO2009050486
OPPOSITIONWO2011152566
OPPOSITIONWO2013080561
SEARCHDE102006062250
SEARCHEP1749538
SEARCHEP1955706
SEARCHWO2009050486

Non-Patent Literature (NPL) Citations (97) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- A. J. MACPHERSON; N. L. HARRIS, NAT REV IMMUNOL, (200406), vol. 4, page 478-
DESCRIPTION- A. M. THORNTON ET AL., J IMMUNOL, (20100401), vol. 184, page 3433-
DESCRIPTION- C. L. MAYNARD ET AL., NAT IMMUNOL, (200709), vol. 8, page 931-
DESCRIPTION- D'ANGELO ET AL., J. BIOL. CHEM., (2001), vol. 276, pages 11347 - 11353-
DESCRIPTION- D. BOUSKRA ET AL., NATURE, (20081127), vol. 456, page 507-
DESCRIPTION- FAGARASAN ET AL., SCIENCE, (20021115), vol. 298, page 1424-
DESCRIPTION- G. MATTEOLI ET AL., GUT, (201005), vol. 59, page 595-
DESCRIPTION- HEIDINGER ET AL., BIOL. CHEM., (2006), vol. 387, pages 69 - 78-
DESCRIPTION- HONDA ET AL., J EXP MED, (20010305), vol. 193, page 621-
DESCRIPTION- ITOH, K.; MITSUOKA, T., "Characterization of clostridia isolated from faeces of limited flora mice and their effect on caecal size when associated with germ-free mice", LAB. ANIMALS, (1985), vol. 19, pages 111 - 118, XP002657282-
DESCRIPTION- IVANOV, II ET AL., CELL, (20091030), vol. 139, page 485-
DESCRIPTION- IVANOV, II ET AL., CELL HOST MICROBE, (20081016), vol. 4, page 337-
DESCRIPTION- J. J. CEBRA, AM J CLIN NUTR, (199905), vol. 69, page 1046S-
DESCRIPTION- J. L. ROUND; S. K. MAZMANIAN, NAT REV IMMUNOL, (200905), vol. 9, page 313-
DESCRIPTION- K. ATARASHI ET AL., NATURE, (20081009), vol. 455, page 808-
DESCRIPTION- K. M. MASLOWSKI ET AL., NATURE, (20091029), vol. 461, page 1282-
DESCRIPTION- L. F. LU; A. RUDENSKY, GENES DEV, (20090601), vol. 23, page 1270-
DESCRIPTION- M. A. CUROTTO DE LAFAILLE; J. J. LAFAILLE, IMMUNITY, (200905), vol. 30, page 626-
DESCRIPTION- M. BOIRIVANT; I. J. FUSS; A. CHU; W. STROBER, J EXP MED, (19981116), no. 1929, page 188-
DESCRIPTION- M. J. BARNES; F. POWRIE, IMMUNITY, (20090918), vol. 31, page 401-
DESCRIPTION- M. N. KWEON ET AL., J IMMUNOL, (20050401), vol. 174, page 4365-
DESCRIPTION- N. H. SALZMAN ET AL., NAT IMMUNOL, vol. 11, page 76-
DESCRIPTION- RAKOFF-NAHOUM; J. PAGLINO; F. ESLAMI-VARZANEH; S. EDBERG; R. MEDZHITOV, CELL, (20040723), vol. 118, page 229-
DESCRIPTION- S. L. SANOS ET AL., NAT IMMUNOL, (200901), vol. 10, page 83-
DESCRIPTION- S. MANICASSAMY ET AL., SCIENCE, (20100813), vol. 329, page 849-
DESCRIPTION- S. SAKAGUCHI; T. YAMAGUCHI; T. NOMURA; M. ONO, CELL, (20080530), vol. 133, page 775-
DESCRIPTION- S. WIRTZ; C. NEUFERT; B. WEIGMANN; M. F. NEURATH, NAT PROTOC, (2007), vol. 2, page 541-
DESCRIPTION- T. AEBISCHER ET AL., "Vaccination prevents Helicobacter pylori-induced alterations of the gastric flora in mice", FEMS IMMUNOL. MED. MICROBIOL., (2006), vol. 46, pages 221 - 229-
DESCRIPTION- V. GABORIAU-ROUTHIAU ET AL., IMMUNITY, (20091016), vol. 31, page 677-
DESCRIPTION- W. S. GARRETT ET AL., CELL, (20071005), vol. 131, page 33-
DESCRIPTION- Y. P. RUBTSOV ET AL., IMMUNITY, (200804), vol. 28, page 546-
DESCRIPTION- YU ET AL., GENES DEV., (2000), vol. I4, pages 163 - 176-
EXAMINATION- ORIANA ROSSI ET AL, "Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses", SCIENTIFIC REPORTS, (20160104), vol. 6, doi:10.1038/srep18507, page 18507, XP055351788
OPPOSITION- 14th International Congress of Immunology abstract book-
OPPOSITION- 14th International Congress of Immunology, Kyoto, (20100822), XP055911236-
OPPOSITION- Atarashi Koji, Takeshi Tanoue, Kenya Honda, "Regulation of colonic regulatory T cells by Clostridium species", 14th international congress of immunology, (20100822), XP055911236-
OPPOSITION- BRUCE ROBERTS, "Generation and Development of defined Microbial drug products", 1st Microbiome Drug Development Summit, (20160628), pages 1 - 17, XP055777427-
OPPOSITION- "Chapter 11. Spore-Forming Gram-PositiveBacilli: Bacillus and Clostridium Species", Jawetz, Melnick, & Adelberg, Medical Microbiology, McGraw Hill, (20120000), pages 1 - 15, XP055402634-
OPPOSITION- "Chapter 18 Clostridia: Sporeforming Anaerobic Bacilli", WELLS C. L. et al., Medical Microbiologyy. 4th ed., Galveston (TX), (19960000), pages 1 - 20, XP055402640-
OPPOSITION- HAYASHI et al., "Phylogenetic Analysis of the Human Gut Microbiota Using 16S rDNA Clone Libraries and Strictly Anaerobic Culture-Based Methods", Microbiol. Immunol., (20020000), vol. 46, pages 535 - 548, XP003017192-
OPPOSITION- HAYASHI H, SAKAMOTO M, BENNO Y, "Phylogenetic analysis of the human gut microbiota using 16S rDNA clone libraries and strictly anaerobic culture-based methods", Microbiology and Immunology, Center for Academic Publications Japan|, JP, JP , (20020101), vol. 46, no. 8, ISSN 0385-5600, pages 535 - 548, XP003017192-
OPPOSITION- Honda Kenya, Koji Atarashi, Takeuchi Tanoue, Tatsuichiro Shima, "Regulation of T Cell Responses by Intestinal Commensal Bacteria", Journal of Intestinal Microbiology, (20110401), vol. 25, no. 2, pages 103 - 104, XP055982048-
OPPOSITION- "International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10)", who, (20160000), URL: www.as.who.int/classifications/icd10/browse/2016/en#/I-
OPPOSITION- ITOH et al., "Characterization of clostridia isolated from faeces of limited flora mice and their effect on caecal size when associated with germ-free mice", Laboratory Animals, (19850400), vol. 19, no. 2, pages 111 - 118, XP002657282-
OPPOSITION- ITOH K. et al., "Characterization of clostridia isolated from faeces of limited flora mice and their effect on caecal size when associated with germ-free mice", Lab. Animals, (19850000), vol. 19, pages 111 - 118, XP002657282-
OPPOSITION- Itoh K, Mitsuoka T, "Characterization of clostridia isolated from faeces of limited flora mice and their effect on caecal size when associated with germ-free mice", LABORATORY ANIMALS., LABORATORY ANIMALS, LONDON., GB, GB , (19850401), vol. 19, no. 2, ISSN 0023-6772, pages 111 - 118, XP002657282-
OPPOSITION- Janeway Charles, Travers Paul, Walport Mark, Shlomchik M., "Pathogens", Janeway in Immunoblology. 6th ed.,, (20040101), page 414, XP055982030-
OPPOSITION- O'garra, Et Al, "IL-10 producing and naturally occuring cd4+ tregs limiting collateral damage", J. Clin. Invest., (20040101), vol. 114, pages 1372 - 1378, XP055402442-
OPPOSITION- Yokota A., H. Takeuchi Y. Ohoka S. Song M. Iwata, "WS/PP-064-01 Vitamin A status influences functional differentiation of T cells through affecting the function of intestinal dendritic cells", Internacional Immunology. 14th International Congress of Immunology, (20100801), vol. 22, no. Suppl 1 Pt 3, pages 131 - 133, XP055982038-
OPPOSITION- Carvalho Frédéric A., Barnich Nicolas, Sauvanet Pierre, Darcha Claude, Gelot Agathe, Darfeuille-Michaud Arlette, "Crohnʼs disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin", HHS PUBLIC ACCESS AUTHOR MANUSCRIPT, Lippincott Williams & Wilkins, US, US , (20080801), vol. 14, no. 8, doi:10.1002/ibd.20423, ISSN 1078-0998, pages 1051 - 1060, XP055982067
OPPOSITION- Creg J. Workman ; Andrea L. Szymczak-Workman ; Lauren W. Collison ; Meenu R. Pillai ; Dario A. A. Vignali, "The development and function of regulatory T cells", Cellular and Molecular Life Sciences, Birkhäuser-Verlag, Ba, Ba , (20090424), vol. 66, no. 16, doi:10.1007/s00018-009-0026-2, ISSN 1420-9071, pages 2603 - 2622, XP019736002
OPPOSITION- WORKMAN CJ et al., "The development and function of regulatory T cells", Cell Mol Life Sci., (20090000), vol. 66, no. 16, doi:10.1007/s00018-009-0026-2, pages 2603 - 2622, XP019736002
OPPOSITION- WORKMAN CJ et al., "The Development and Function of Regulatory T Cells", Cell Mol Life Sci., (20090424), vol. 66, no. 16, pages 2603 - 2622, XP019736002
OPPOSITION- Ana M. Sanchez, Yang Yiping, "The role of natural regulatory T cells in infection", NIH Public Access Author Manuscript, (20110401), vol. 49, no. 1-3, doi:10.1007/s12026-010-8176-8, pages 1 - 12, XP055598600
OPPOSITION- Rick M Maizels, Katherine A Smith, "Chapter 3 Regulatory T Cells in Infection", Advances in Immunology, (20110101), pages 74 - 136, doi:10.1016/B978-0-12-387827-4.00003-6, XP055598608
OPPOSITION- BAKKEN et al., "Fecal bacteriotherapy for recurrent Clostridium difficile infection", Anaerobe, (20090101), vol. 15, no. 6, pages 285 - 289, XP009161367
OPPOSITION- Bakken Johan S, "Fecal bacteriotherapy for recurrent Clostridium difficile infection.", Anaerobe, (20090101), vol. 15, no. 6, doi:10.1016/j.anaerobe.2009.09.007, ISSN 1095-8274, pages 285 - 289, XP009161367
OPPOSITION- JOHAN S . BAKKEN et al., "Fecal bacteriotherapy for recurrent Clostridium difficile infection", Anaerobe, (20090000), vol. 15, doi:10.1016/j.anaerobe.2009.09.007, pages 285 - 289, XP002754036
OPPOSITION- Lupp Claudia, Robertson Marilyn L., Wickham Mark E., Sekirov Inna, Champion Olivia L., Gaynor Erin C., Finlay B. Brett, "Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae", Cell Host & Microbe, Elsevier, NL, NL , (20070801), vol. 2, no. 2, doi:10.1016/j.chom.2007.06.010, ISSN 1931-3128, pages 119 - 129, XP055982054
OPPOSITION- GABORIAU-ROUTHIAU et al., "The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T cell Responses", Immunity, (20091000), vol. 31, no. 4, doi:10.1016/j.immuni.2009.08.020, pages 677 - 689, XP055005245
OPPOSITION- Valérie Gaboriau-Routhiau, Sabine Rakotobe, Emelyne Lécuyer, Imke Mulder, Annaïg Lan, Chantal Bridonneau, Violaine Rochet, Annamaria Pisi, Marianne De Paepe, Giovanni Brandi, Gérard Eberl, Johannes Snel, Denise Kelly, Nadine Cerf-Bensussan, "The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses", Immunity, Cell Press, (20091001), vol. 31, no. 4, doi:10.1016/j.immuni.2009.08.020, ISSN 10747613, pages 677 - 689, XP055005245
OPPOSITION- KELLY D. et al., "Commensal gut bacteria: mechanisms of immune modulation", Trends in Immunology, (20050601), vol. 26, no. 6, pages 326 - 333, XP004938753
OPPOSITION- ATARASHI K. et al., "Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota", Nature, (20130710), vol. 500, no. 7461, pages 232 - 236, XP037227993
OPPOSITION- Atarashi Koji; Tanoue Takeshi; Oshima Kenshiro; Suda Wataru; Nagano Yuji; Nishikawa Hiroyoshi; Fukuda Shinji; Saito Takuro; Narushima Seiko; Hase Koji; Kim Sangwan; Fritz Joëlle V.; Wilmes Paul; Ueha Satoshi; Matsushima Kouji; Ohno Hiroshi; Olle Bernat; Sakaguchi Shimon; Taniguchi Tadatsugu; Morita Hidetoshi; Hattori Masahira; Honda Kenya, "Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota", Nature, Nature Publishing Group UK, London, London, (20130710), vol. 500, no. 7461, doi:10.1038/nature12331, ISSN 0028-0836, pages 232 - 236, XP037227993
OPPOSITION- Yasmine Belkaid, Barry T Rouse, "Natural regulatory T cells in infectious disease", Nature Immunology, Nature America Inc., (20050401), vol. 6, no. 4, doi:10.1038/ni1181, ISSN 15292908, pages 353 - 360, XP055206505
OPPOSITION- ZHOU et al., "Total fecal microbiota transplantation alleviates high fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota", Scientific Reports ( Nature), (20170508), vol. 7, no. 1, pages 1 - 11, XP055777414
OPPOSITION- ROSSI et al., "Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL -10 in human and murine dendritic cells and modulates T cell responses", Sci Rep., (20160000), vol. 6, doi:10.1038/srep18507, page 18507, XP055351788
OPPOSITION- FRANK et al., "Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases", PNAS, (20070000), vol. 104, no. 34, doi:10.1073/pnas.0706625104, pages 13780 - 13785, XP055050956
OPPOSITION- SOKOL et al., "Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients", Proceedings of the National Academy of Sciences , USA, (20080000), vol. 105, no. 43, doi:10.1073/PNAS.0804812105, pages 16731 - 16736, XP002579466
OPPOSITION- Jawhara Samir; Poulain Daniel, "Saccharomyces boulardii decreases inflammation and intestinal colonization by Candida albicans in a mouse model of chemically-induced colitis", Medical mycology, Informa Healthcare, Abingdon, Abingdon , (20071201), vol. 45, no. 8, doi:10.1080/13693780701523013, ISSN 1369-3786, pages 691 - 700, XP009101538
OPPOSITION- AAS J. et al., "Recurrent Clostridium difficile Colitis: Case Series Involving 18 Patients Treated with Donor Stool Administered via a Nasogastric Tube", CID, (20030301), vol. 36, no. 5, pages 580 - 585, XP055043539
OPPOSITION- Johannes Aas, Charles E. Gessert, Johan S. Bakken, "Recurrent Clostridium difficile Colitis: Case Series Involving 18 Patients Treated with Donor Stool Administered via a Nasogastric Tube", Clinical Infectious Diseases, (20030301), vol. 36, no. 5, doi:10.1086/367657, ISSN 10584838, pages 580 - 585, XP055043539
OPPOSITION- Keynan, Et Al, "The Role of Regulatory T Cells in Chronic and Acute Viral Infections", Clinical Infectious Diseases, (20080401), vol. 46, doi:10.1086/529379, pages 1046 - 1052, XP055402435
OPPOSITION- Borody T J, et al, "Treatment of ulcerative colitis using fecal bacteriotherapy", JOURNAL OF CLINICAL GASTROENTEROLOGY., RAVEN PRESS LTD., NEW YORK, NY., US, US , (20030101), vol. 37, no. 1, doi:10.1097/00004836-200307000-00012, ISSN 0192-0790, pages 42 - 47, XP008093566
OPPOSITION- M. D. Collins, P. A. Lawson, A. Willems, J. J. Cordoba, J. Fernandez-Garayzabal, P. Garcia, J. Cai, H. Hippe, J. A. E. Farrow, "The Phylogeny of the Genus Clostridium: Proposal of Five New Genera and Eleven New Species Combinations", International Journal of Systematic Bacteriology, (19941001), vol. 44, no. 4, doi:10.1099/00207713-44-4-812, ISSN 00207713, pages 812 - 826, XP055107539
OPPOSITION- CLAVEL et al., "Survival of Bacillus cereus spores and vegetative cells in acid media simulating human stomach", Journal of Applied Microbiology, vol. 97, doi:10.1111/j.1365-2672.2004.02292.x, pages 214 - 219, XP055365130
OPPOSITION- MOMOSE et al., "16S rRNA gene sequence-based analysis of clostridia related to conversion of germfree mice to the normal state", Journal of Applied Microbiology, (20090000), vol. 107, doi:10.1111/j.1365-2672.2009.04431.x, pages 2088 - 2097, XP055402299
OPPOSITION- Momose Y, Et Al, "16 rRNA gene sequence based analysis of clostridia related to conversion of germfree mice to the normal state", Journal of Applied Microbiology, (20090101), doi:10.1111/j.1365-2672.2009.04431.x, pages 2088 - 2097, XP055402299
OPPOSITION- Petra Louis, Et Al, "Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine", FEMS Microbiology Letters, No longer published by Elsevier, (20090501), vol. 294, no. 1, doi:10.1111/j.1574-6968.2009.01514.x, ISSN 0378-1097, pages 1 - 8, XP055397860
OPPOSITION- ATARASHI et al., "Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species", Science, (20111223), vol. 331, no. 6015, pages 337 - 341, XP055178447
OPPOSITION- K. Atarashi, Tanoue T., Shima T., Imaoka A., Kuwahara T., Momose Y., Cheng G., Yamasaki S., Saito T., Ohba Y., Taniguchi T., Takeda K., Hori S., Ivanov I. I., Umesaki Y., Itoh K., Honda K., "Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species - Supporting Online Material", Science, American Association for the Advancement of Science, (20110121), vol. 331, no. 6015, doi:10.1126/science.1198469, ISSN 00368075, pages 337 - 341, XP055178447
OPPOSITION- SGHIR ABDELGHANI ET AL, "Quantification of bacterial groups within human fecal flora by oligonucleotide probe hybridization.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, American Society for Microbiology, US, US , (20000501), vol. 66, no. 5, doi:10.1128/AEM.66.5.2263-2266.2000, ISSN 0099-2240, pages 2263 - 2266, XP002166836
OPPOSITION- SGHIR et al., "Quantification of Bacterial Groups within Human Fecal Flora by Oligonucleotide Probe Hybridization", Applied and Environmental Microbiology, (20000000), vol. 66, no. 5, doi:10.1128/AEM.66.5.2263-2266.2000, pages 2263 - 2266, XP002166836
OPPOSITION- KARIMI et al., "Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice", Am J Respir Crit Care Med, (20090201), vol. 179, no. 3, doi:10.1164/rccm.200806-951OC, pages 186 - 93, XP055005126
OPPOSITION- KAKIHANA K. et al., "Fecal microbiota transplantation for patients with steroid-resistant acute graft-versus-host disease of the gut", Blood, (20161020), vol. 128, no. 16, pages 2083 - 2088, XP055402621
OPPOSITION- KROGIUS-KURIKKA et al., "Large scale multiplex PCR improves pathogen detection by DNA microarrays", BMC Microbiology, (20090103), vol. 9, no. 1, pages 1 - 14, XP021048175
OPPOSITION- Itoh, Et Al, "Intestinal bacteria antagonistic to Clostridium difficile in mice", Lab Animals, (19870101), vol. 21, doi:10.1258/002367787780740662, pages 20 - 25, XP055402613
OPPOSITION- ITOH K. et al, "Intestinal bacteria antagonistic to Clostridium difficile in mice", Laboratory Animals, (19870000), vol. 21, pages 20 - 25, XP055402613
OPPOSITION- Biddle Amy S., Et Al, "The complete genome sequence of Clostridium indolis DSM 755T", Standards in Genomic Sciences, (20140101), vol. 9, no. 3, doi:10.4056/sigs.5281010, pages 1089 - 1104, XP055981585
SEARCH- ITOH K ET AL, "Characterization of clostridia isolated from faeces of limited flora mice and their effect on caecal size when associated with germ-free mice.", LABORATORY ANIMALS APR 1985 LNKD- PUBMED:3889493, (198504), vol. 19, no. 2, ISSN 0023-6772, pages 111 - 118, XP002657282 [YD] 1,3-15 * the whole document *-
SEARCH- VALÉRIE GABORIAU-ROUTHIAU ET AL, "The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses", IMMUNITY, (20091001), vol. 31, no. 4, doi:10.1016/j.immuni.2009.08.020, ISSN 1074-7613, pages 677 - 689, XP055005245 [YD] 1,3-15 * the whole document * * page 681, column r * * page 682; figure 5 *
SEARCH- KOJI ATARASHI ET AL, "Microbiotal influence on T cell subset development", SEMINARS IN IMMUNOLOGY, (20110401), vol. 23, no. 2, doi:10.1016/j.smim.2011.01.010, ISSN 1044-5323, pages 146 - 153, XP055005114
SEARCH- SOKOL HARRY ET AL, "Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, WASHINGTON, DC; US, vol. 105, no. 43, doi:10.1073/PNAS.0804812105, ISSN 0027-8424, (20081028), pages 16731 - 16736, (20081020), XP002579466 [Y] 1,3-15 * the whole document *
SEARCH- T. CLAVEL ET AL, "Survival of Bacillus cereus spores and vegetative cells in acid media simulating human stomach", JOURNAL OF APPLIED MICROBIOLOGY., GB, (20040701), vol. 97, no. 1, doi:10.1111/j.1365-2672.2004.02292.x, ISSN 1364-5072, pages 214 - 219, XP055365130 [Y] 1,3-15 * the whole document *
SEARCH- K. ATARASHI ET AL, "Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species", SCIENCE, (20110121), vol. 331, no. 6015, doi:10.1126/science.1198469, ISSN 0036-8075, pages 337 - 341, XP055005026
SEARCH- K. KARIMI ET AL, "Lactobacillus reuteri-induced Regulatory T cells Protect against an Allergic Airway Response in Mice", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, (20090201), vol. 179, no. 3, doi:10.1164/rccm.200806-951OC, ISSN 1073-449X, pages 186 - 193, XP055005126 [Y] 1,3-15 * the whole document *
SEARCH- TANOUE TAKESHI ET AL., "Immune responses to gut microbiota-commensals and pathogens", GUT MICROBES, (20100701), vol. 1, no. 4, pages 224 - 233, XP002657283

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