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Mrna Therapy For Argininosuccinate Synthetase Deficiency - EP3501605

The patent EP3501605 was granted to Translate BIO on Jun 28, 2023. The application was originally filed on Oct 22, 2014 under application number EP18205194A. The patent is currently recorded with a legal status of "Revoked".

EP3501605

TRANSLATE BIO
Application Number
EP18205194A
Filing Date
Oct 22, 2014
Status
Revoked
Jul 11, 2025
Grant Date
Jun 28, 2023
External Links
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Patent Citations (44) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication NumberPublication Link
DESCRIPTIONUS4373071
DESCRIPTIONUS4401796
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DESCRIPTIONUS4458066
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DESCRIPTIONUS4973679
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DESCRIPTIONUS5171678
DESCRIPTIONUS5262530
DESCRIPTIONUS5334761
DESCRIPTIONUS5700642
DESCRIPTIONUS5744335
DESCRIPTIONUS5885613
DESCRIPTIONUS8093367
DESCRIPTIONUS8304529
DESCRIPTIONWO2005121348
DESCRIPTIONWO2010042877
DESCRIPTIONWO2010053572
DESCRIPTIONWO2011068810
DESCRIPTIONWO2012170889
DESCRIPTIONWO2012170930
DESCRIPTIONWO2013063468
OPPOSITIONUS2013259924
OPPOSITIONWO2010053572
OPPOSITIONWO2011068810
OPPOSITIONWO2012170889
OPPOSITIONWO2012170930
OPPOSITIONWO2013063468
OPPOSITIONWO2013149140
OPPOSITIONWO2013151666
OPPOSITIONWO2013185069
OPPOSITIONWO2014144196
SEARCHWO2011068810
SEARCHWO2012075040
SEARCHWO2012170889
SEARCHWO2013063468
SEARCHWO2013149140
SEARCHWO2013185069
SEARCHWO2014144196

Non-Patent Literature (NPL) Citations (42) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference TextLink
DESCRIPTION- BEHR et al., Proc. Nat.'l Acad. Sci., (19890000), vol. 86, page 6982-
DESCRIPTION- BLOOMFIELD, Ann. Rev. Biophys. Bioeng., (19810000), vol. 10, pages 421 - 150-
DESCRIPTION- FEIGNER et al., Proc. Nat'l Acad. Sci., (19870000), vol. 84, page 7413-
DESCRIPTION- GAO et al., Biochem. Biophys. Res. Comm., (19910000), vol. 179, page 280-
DESCRIPTION- GRUDZIEN, E. et al., RNA, (20040000), vol. 10, pages 1479 - 1487-
DESCRIPTION- GRUDZIEN-NOGALSKA, E. et al., RNA, (20070000), vol. 13, pages 1745 - 1755-
DESCRIPTION- HEYES, J. et al., J Controlled Release, (20050000), vol. 107, pages 276 - 287-
DESCRIPTION- JEMIELITY, J. et al., RNA, (20030000), vol. 9, pages 1108 - 1122-
DESCRIPTION- KLIBANOV et al., FEBS Letters, (19900000), vol. 268, no. 1, pages 235 - 237-
DESCRIPTION- LASIC et al., FEBS Lett., (19920000), vol. 312, pages 255 - 258-
DESCRIPTION- LASIC, Trends Biotechnol., (19980000), vol. 16, pages 307 - 321-
DESCRIPTION- MORRISSEY, DV. et al., Nat. Biotechnol., (20050000), vol. 23, no. 8, pages 1003 - 1007-
DESCRIPTION- Remington's Pharmaceutical Sciences, Mack Publishing Co.-
DESCRIPTION- SEMPLE et al., Nature Biotech., (20100000), vol. 28, pages 172 - 176-
DESCRIPTION- S. M. BERGE et al., "pharmaceutically acceptable salts", J. Pharmaceutical Sciences, (19770000), vol. 66, pages 1 - 19-
DESCRIPTION- WOLF et al., BioTechniques, (19970000), vol. 23, page 139-
DESCRIPTION- YOKOE et al., Nature Biotechnology, (19960000), vol. 14, pages 1252 - 1256-
DESCRIPTION- HEYES, J.; PALMER, L.; BREMNER, K.; MACLACHLAN, I., "Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids", J. Contr. Rel., (20050000), vol. 107, doi:doi:10.1016/j.jconrel.2005.06.014, pages 276 - 287, XP008157522
DESCRIPTION- SEMPLE, S.C. et al., "Rational Design of Cationic Lipids for siRNA Delivery", Nature Biotech., (20100000), vol. 28, doi:doi:10.1038/NBT.1602, pages 172 - 176, XP002633693
DESCRIPTION- LOVE, K.T. et al., "Lipid-like materials for low-dose in vivo gene silencing", PNAS, (20100000), vol. 107, doi:doi:10.1073/pnas.0910603106, pages 1864 - 1869, XP055077922
DESCRIPTION- FECHTER, P.; BROWNLEE, G.G., "Recognition of mRNA cap structures by viral and cellular proteins", J. Gen. Virology, (20050000), vol. 86, doi:doi:10.1099/VIR.0.80755-0, pages 1239 - 1249, XP002516933
DESCRIPTION- JEMIELITY, J. et al., "Novel 'anti-reverse' cap analogs with superior translational properties", RNA, (20030000), vol. 9, doi:doi:10.1261/rna.5430403, pages 1108 - 1122, XP002466761
OPPOSITION- Anonymous, "Firefly luciferase reporter vector pGL4.10[luc2], complete sequence", Nucleotide, (20041108), Database accession no. AY738222 , URL: NCBI, XP093208716-
OPPOSITION- Kuhn Andreas N; Beissert Tim; Simon Petra; Vallazza Britta; Buck Janina; Davies Brian P; Tuereci Oezlem; Sahin Ugur, "mRNA as a Versatile Tool for Exogenous Protein Expression", Current Gene Therapy, Bentham Science Publishers Ltd., NL, NL , (20121001), vol. 12, no. 5, ISSN 1566-5232, pages 347 - 361, XP008159357-
OPPOSITION- Maclachlan Ian, Stanley T. Crooke, "CHAPTER 9 Liposomal Formulations for Nucleic Acid Delivery", Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition, CRC Press, (20070725), pages 237 - 270, XP093180362-
OPPOSITION- Schlich Michele, Palomba Roberto, Costabile Gabriella, Mizrahy Shoshy, Pannuzzo Martina, Peer Dan, Decuzzi Paolo, "Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles", Bioengineering & Translational Medicine, (20210501), vol. 6, no. 2, doi:10.1002/btm2.10213, ISSN 2380-6761, page e10213, XP093180364
OPPOSITION- Patejunas Gerald, Bradley Allan, Beaudet Arthur L., O'brien William E., "Generation of a mouse model for citrullinemia by targeted disruption of the argininosuccinate synthetase gene", Somatic Cell and Molecular Genetics, Kluwer Academic, (19940101), vol. 20, no. 1, doi:10.1007/BF02257486, ISSN 0740-7750, pages 55 - 60, XP093180357
OPPOSITION- Hassett Kimberly J., Benenato Kerry E., Jacquinet Eric, Lee Aisha, Woods Angela, Yuzhakov Olga, Himansu Sunny, Deterling Jessica, Geilich Benjamin M., Ketova Tatiana, Mihai Cosmin, Lynn Andy, Mcfadyen Iain, Moore Melissa J., Senn Joseph J., Stanton Matthew G., Almarsson Örn, Ciaramella Giuseppe, Brito Luis A., "Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines", Molecular Therapy-Nucleic Acids, Cell Press, US, US , (20190415), vol. 15, doi:10.1016/j.omtn.2019.01.013, ISSN 2162-2531, pages 1 - 11, XP055815007
OPPOSITION- Semple Sean C.; Klimuk Sandra K.; Harasym Troy O.; Dos Santos Nancy; Ansell Steven M.; Wong Kim F.; Maurer Norbert; Stark Holger; Cullis Pieter R.; Hope Michael J.; Scherrer Peter, "Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures", Biochimica et Biophysica Acta, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL , (20160613), vol. 1510, no. 1, doi:10.1016/S0005-2736(00)00343-6, ISSN 0005-2736, pages 152 - 166, XP085070789
OPPOSITION- Akinc Akin; Maier Martin A.; Manoharan Muthiah; Fitzgerald Kevin; Jayaraman Muthusamy; Barros Scott; Ansell Steven; Du Xinyao; Hope Michael J.; Madden Thomas D.; Mui Barbara L.; Semple Sean C.; Tam Ying K.; Ciufolini Marco; Witzigmann Dominik; Kulkarni Jayesh A.; van der Meel Roy; Cullis Pieter R., "The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs", nature nanotechnology, Nature Pub. Group, Inc., London, London , (20191201), vol. 14, no. 12, doi:10.1038/s41565-019-0591-y, ISSN 1748-3387, pages 1084 - 1087, XP036953174
OPPOSITION- Carrasco Manuel J., Alishetty Suman, Alameh Mohamad-Gabriel, Said Hooda, Wright Lacey, Paige Mikell, Soliman Ousamah, Weissman Drew, Cleveland Thomas E., Grishaev Alexander, Buschmann Michael D., "Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration", Communications Biology, Nature Publishing Group UK, (20210811), vol. 4, no. 1, doi:10.1038/s42003-021-02441-2, ISSN 2399-3642, page :956, XP093180360
OPPOSITION- Love Kevin T., Mahon Kerry P., Levins Christopher G., Whitehead Kathryn A., Querbes William, Dorkin J. Robert, Qin June, Cantley William, Qin Liu Liang, Racie Timothy, Frank-Kamenetsky Maria, Yip Ka Ning, Alvarez Rene, Sah Dinah W. Y., De Fougerolles Antonin, Fitzgerald Kevin, Koteliansky Victor, Akinc Akin, Langer Robert, Anderson Daniel G., "Lipid-like materials for low-dose, in vivo gene silencing", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20100202), vol. 107, no. 5, doi:10.1073/pnas.0910603106, ISSN 0027-8424, pages 1864 - 1869, XP093143656
OPPOSITION- Y. Dong, K. T. Love, J. R. Dorkin, S. Sirirungruang, Y. Zhang, D. Chen, R. L. Bogorad, H. Yin, Y. Chen, A. J. Vegas, C. A. Alabi, G. Sahay, K. T. Olejnik, W. Wang, A. Schroeder, A. K. R. Lytton-Jean, D. J. Siegwart, A. Akinc, C. Barnes, S. A. Barros, M. Carioto, K. Fitzgerald, J. Hettinger, V. Kumar, T. I. Novobrantseva, J. Qin, W. Querbes, V. Koteliansky, R. Langer, D. G. Anderson, "Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20140318), vol. 111, no. 11, doi:10.1073/pnas.1322937111, ISSN 00278424, pages 3955 - 3960, XP055167076
OPPOSITION- Jayesh A. Kulkarni, Pieter R. Cullis, Roy Van Der Meel, "Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility", Nucleic Acid Therapeutics, Mary Ann Liebert, Inc. Publishers, US, US , (20180601), vol. 28, no. 3, doi:10.1089/nat.2018.0721, ISSN 2159-3337, pages 146 - 157, XP055551908
OPPOSITION- GROTE ANDREAS; HILLER KARSTEN; SCHEER MAURICE; MUENCH RICHARD; NOERTEMANN BERND; HEMPEL DIETMAR C; JAHN DIETER, "JCAT: A NOVEL TOOL TO ADAPT CODON USAGE OF A TARGET GENE TO ITS POTENTIAL EXPRESSION HOST", Nucleic Acids Research, Oxford University Press, GB, GB , (20050701), vol. 33, no. SUPPL. 2, doi:10.1093/nar/gki376, ISSN 0305-1048, pages W526 - W531, XP009081066
OPPOSITION- M. Welch, Villalobos A., Gustafsson C., Minshull J., "You're one in a googol: optimizing genes for protein expression", Journal of The Royal Society Interface, (20090806), vol. 6, no. Suppl_4, doi:10.1098/rsif.2008.0520.focus, ISSN 17425689, pages S467 - S476, XP055019124
OPPOSITION- Stephan Fath,Asli Petra Bauer,Michael Liss,Anne Spriestersbach,Barbara Maertens,Peter Hahn,Christine Ludwig,Frank Schäfer,Marcus Graf,Ralf Wagner, "Multiparameter RNA and Codon Optimization: A Standardized Tool to Assess and Enhance Autologous Mammalian Gene Expression", PLoS ONE, (20110303), vol. 6, no. 3, doi:10.1371/journal.pone.0017596, pages 1 - 14, XP055531212
OPPOSITION- Promrat Kittichai, Wu George Y., Wu Catherine H., "Gene Therapy for Metabolic Diseases of the Liver : ", BIODRUGS, Adis International Ltd., NZ, NZ , (20000301), vol. 13, no. 3, doi:10.2165/00063030-200013030-00003, ISSN 1173-8804, pages 177 - 188, XP093180366
OPPOSITION- Carlos J. Perez et al, "Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes", The American Journal of Pathology, (20101001), vol. 177, no. 4, doi:10.2353/ajpath.2010.100118, ISSN 00029440, pages 1958 - 1968, XP055166915
SEARCH- WANG HONG-XIA ET AL, "N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, (20121220), vol. 166, no. 2, doi:10.1016/J.JCONREL.2012.12.017, ISSN 0168-3659, pages 106 - 114, XP028980435 [Y] 1-10 * the whole document *
SEARCH- JIAN WU ET AL, "Modification of liposomes for liver targeting", JOURNAL OF HEPATOLOGY, (19960601), vol. 24, no. 6, doi:10.1016/S0168-8278(96)80274-1, ISSN 0168-8278, pages 757 - 763, XP055101270 [Y] 1-10 * page 760 - page 761 *
SEARCH- Y. DONG ET AL, "Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20140318), vol. 111, no. 11, doi:10.1073/pnas.1322937111, ISSN 0027-8424, pages 3955 - 3960, XP055167076 [PY] 1-10 * the whole document *

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