Methods For Treating Severe Atopic Dermatitis By Administering An Il-4R Inhibitor - EP3515465

The patent EP3515465 was granted to Regeneron Pharmaceuticals on Feb 7, 2024. The application was originally filed on Sep 21, 2017 under application number EP17777145A. The patent is currently recorded with a legal status of "Granted And Under Opposition".

EP3515465

REGENERON PHARMACEUTICALS
Application Number
EP17777145A
Filing Date
Sep 21, 2017
Status
Granted And Under Opposition
Jan 5, 2024
Publication Date
Feb 7, 2024
External Links
Slate, Register, Google Patents

Patent Summary

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Patent Family

Patent Oppositions (8)

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BRAND MURRAY FULLERNov 7, 2024BRAND MURRAY FULLERADMISSIBLE
DORRIESNov 7, 2024DORRIESADMISSIBLE
DORRIESNov 7, 2024DORRIES, HANS ULRICH , DF-MP DORRIES FRANK-MOLNIA & POHLMANADMISSIBLE
MICHALSKI HUTTERMANN & PARTNER PATENTANWALTE MBBNov 7, 2024-ADMISSIBLE
BOULT WADE TENNANTNov 6, 2024BOULT WADE TENNANTADMISSIBLE
RUMINov 6, 2024TER MEER STEINMEISTER & PARTNERADMISSIBLE
SECERNANov 6, 2024SECERNAADMISSIBLE
BOEHMERT & BOEHMERT ANWALTSPARTNERSCHAFT MBBNov 5, 2024ENGELHARDADMISSIBLE

Patent Citations (12) New

Patent citations refer to prior patents cited during different phases such as opposition or international search.

Citation PhasePublication Number
DESCRIPTIONUS2014072583
DESCRIPTIONUS7186809
DESCRIPTIONUS7605237
DESCRIPTIONUS7608693
DESCRIPTIONUS7638606
DESCRIPTIONUS8092804
DESCRIPTIONUS8679487
DESCRIPTIONUS8877189
DESCRIPTIONUS8945559
OPPOSITIONWO2014039461
OPPOSITIONWO2015127229
OPPOSITIONWO2018057776

Non-Patent Literature (NPL) Citations (66) New

NPL citations refer to non-patent references such as research papers, articles, or other publications cited during examination or opposition phases.

Citation PhaseReference Text
EXAMINATION- RING J. ET AL, "Guidelines for treatment of atopic eczema (atopic dermatitis) Part I", JEADV , THE JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, NL, (20120719), vol. 26, no. 9, doi:10.1111/j.1468-3083.2012.04635.x, pages 1045 - 1060, XP093235834
EXAMINATION- RING J. ET AL, "Guidelines for treatment of atopic eczema (atopic dermatitis) Part II : Guidelines for treatment of atopic eczema", JEADV , THE JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, NL, (20120719), vol. 26, no. 9, doi:10.1111/j.1468-3083.2012.04636.x, ISSN 0926-9959, pages 1176 - 1193, XP055780332
OPPOSITION- 52a - Ich benötige das genaue Datum, an dem der folgende Beitrag über SlideShare veröffentlicht wurde
OPPOSITION- A Garriga, "71st ANNUAL MEETING OF THE AMERICAN ACADEMY OF DERMATOLOGY (AAD)", Drugs of the Future, (20130301), pages 275 - 279, XP055566346
OPPOSITION- Anonymous, "ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015", Regeneron Pharmaceuticals Inc Annual report FORM 10-K, (20160211), pages 1 - 197, XP093238217
OPPOSITION- Anonymous, "ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2015", SEC, (20160409), pages 1 - 143, SEC, URL: https://web.archive.org/web/20160309040527/https://www.sec.gov/Archives/edgar/data/872589/000153217616000045/regn-123115x10k.htm, XP093238228
OPPOSITION- Anonymous, "A Study to Assess the Ecacy and Safety of Dupilumab in Participants With Severe Atopic Dermatitis (AD) That Are Not Controlled With Oral Cyclosporine A (CSA) or for Those Who Cannot Take Oral CSA Because it is Not Medically Advisable", Clinical Trials (NCT02755649), (20160824), pages 1 - 20, Clinical Trials (NCT02755649), URL: https://clinicaltrials.gov/study/NCT02755649?tab=history&a=3#version-content-panel, XP093235759
OPPOSITION- Anonymous, "A Study to Assess the Efficacy and Safety of Dupilumab in Participants With Severe Atopic Dermatitis (AD) That Are Not Controlled With Oral Cyclosporine A (CSA) or for Those Who Cannot Take Oral CSA Because it is Not Medically Advisable", Clinical Trials (NCT02755649), (20200820), pages 1 - 13, XP093238256
OPPOSITION- Anonymous, "CAS: PubChem: DRUG D10354-Dupilumab", (20140214), (20160112), XP055240675
OPPOSITION- Anonymous, "DUPIXENT FDA Approval Call", Sanofi, (20170328), pages 1 - 15, Sanofi , URL: /https://www.sanofi.com/assets/dotcom/content-app/events/investor-presentation/2017/Dupixent_FDA_Approval_Investor_call_FINAL.pdf, XP093235857
OPPOSITION- Anonymous, "HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use DUPIXENT safely and effectively. See full prescribing information for DUPIXENT", FDA, (20170301), pages 1 - 34, XP093238191
OPPOSITION- Anonymous, " International Nonproprietary Names for Proposed Pharmaceutical Substances (INN).Proposed: List 108", WHO Drug Information, (20120101), vol. 26, no. 4, pages 401 - 472, XP093196048
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OPPOSITION- Anonymous, "REGENERON AND SANOFI ANNOUNCE POSITIVE DUPILUMAB TOPLINE RESULTS FROM TWO PHASE 3 TRIALS IN INADEQUATELY CONTROLLED MODERATE-TO-SEVERE ATOPIC DERMATITIS PATIENTS", Regeneron, pages 1 - 4, Regeneron, URL: https://investor.regeneron.com/news-releases/news-release-details/regeneron-and-sanofi-announce-positive-dupilumab-topline-results, XP093235827
OPPOSITION- Anonymous, "REGENERON AND SANOFI ANNOUNCE THAT DUPILUMAB USED WITH TOPICAL CORTICOSTEROIDS (TCS) WAS SUPERIOR TO TREATMENT WITH TCS ALONE IN LONG-TERM PHASE 3 TRIAL IN INADEQUATELY CONTROLLED MODERATE-TO-SEVERE ATOPIC DERMATITIS PATIENTS", Regeneron, pages 1 - 4, Regeneron, URL: https://newsroom.regeneron.com/news-releases/news-release-details/regeneron-and-sanofi-announce-dupilumab-used-topical, XP093235832
OPPOSITION- Anonymous, "Sanofi and Regeneron Announce Positive Study Results for Dupixent ® (dupilumab) in Patients With Moderate-to-Severe Atopic Dermatitis", Sanofi, (20170101), pages 1 - 5, Sanofi, URL: https://www.sanofi.com/en/media-room/press-releases/2017/2017-09-16-06-15-00-1123825, XP093238194
OPPOSITION- Anonymous, "Sanofi and Regeneron Report Positive Proof- of-Concept Data for Dupilumab, an IL -4R alpha Antibody, in Atopic Dermatitis", Regeneron, (20130302), pages 1 - 4, Regeneron, URL: https://newsroom.regeneron.com/news-releases/news-release-details/sanofi-and-regeneron-report-positive-proof-concept-data, (20190308), XP055566341
OPPOSITION- Anonymous, "Study of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis (SOLO 1)", Clinical trials Version 17, (20160816), pages 1 - 8, XP093235820
OPPOSITION- Anonymous, "Study of Dupilumab (REGN668/SAR231893) Monotherapy Administered to Adult Patients With Moderate-toSevere Atopic Dermatitis (SOLO 2) Version 15 ", Clinical Trials NCT02277769, (20160226), pages 1 - 6, XP093235822
OPPOSITION- Anonymous, "Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis (CHRONOS) Version 17", Clinical trials - NCT02260986, (20160902), pages 1 - 7, XP093235829
OPPOSITION- Anonymous, "Study to Assess the Safety of Dupilumab (REGN668/SAR231893) Administered Concomitantly With Topical Corticosteroids (TCS) in Patients With Moderate-to-severe Atopic Dermatitis (AD)", Clinical Trials NCT01639040 Version 6, (20230927), pages 1 - 4, XP093235817
OPPOSITION- D09- Supplementary appendix
OPPOSITION- D19a-Supplementary Appendix
OPPOSITION- D19b - Protocol
OPPOSITION- D37- EMA. Annex I Summary of product characteristics for dupilumab
OPPOSITION- D3a-Protocol
OPPOSITION- D3 - Supplementary Appendix
OPPOSITION- D50-Patentee's submission dated 2 December 2020
OPPOSITION- D51-Patentee's submission dated 24 August 2022
OPPOSITION- D52b - need to know the exact date on which the following post was published on SlideShare
OPPOSITION- D55- Early Access to Medicines Scheme - Information for Applicants
OPPOSITION- D56a- Official confirmation from ClinicalTrials.gov that D11 was published no later than April 26, 2016
OPPOSITION- D58 - Dupixent 200 mg solution for injection in pre-filled pen
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