| DESCRIPTION | - BUNN P.A. et al., Clin Cancer Res., (20010000), vol. 7, pages 3239 - 3250 |
| DESCRIPTION | - CHIORINI et al., J. Virol., (19970000), vol. 71, pages 6823 - 6833 |
| DESCRIPTION | - COSSET et al., J Virol, (19950000), vol. 69, pages 7430 - 7436 |
| DESCRIPTION | - DUARTE S et al., J Control Release, (20110000), vol. 149, no. 3, pages 264 - 272 |
| DESCRIPTION | - FIERER, PNAS, (20140000), vol. 111, pages E1176 - 1181 |
| DESCRIPTION | - GAO et al., Curr. Gen. Ther., (20050000), vol. 5, no. 3, pages 285 - 297 |
| DESCRIPTION | - HABASHY HO et al., Breast Cancer Res Treat, vol. 119, no. 2, pages 283 - 293 |
| DESCRIPTION | - HEIDER KH et al., Cancer Immunol Immunother, (20040000), vol. 53, pages 567 - 579 |
| DESCRIPTION | - HEIMBERGER AB et al., Expert Opin Biol Ther, (20090000), vol. 9, pages 1087 - 1098 |
| DESCRIPTION | - JIALT et al., Cancer Res., (20030000), vol. 63, pages 3257 - 3262 |
| DESCRIPTION | - KARASUYAMA et al., J. Exp. Med., (19890000), vol. 169, page 13 |
| DESCRIPTION | - KEEBLE et al., Angew Chem Int Ed Engl, (20170000), vol. 56, pages 16521 - 16525 |
| DESCRIPTION | - KERN et al., J Virol., (20030000), vol. 77, no. 20, pages 11072 - 81 |
| DESCRIPTION | - KERN JA et al., Am J Respir Cell Mol Biol, (19930000), vol. 9, pages 448 - 454 |
| DESCRIPTION | - KOTIN et al., Hum. Gene Ther., (19940000), vol. 5, page 793 |
| DESCRIPTION | - LENG A et al., Tumour Biol., (20130000), vol. 32, pages 1103 - 1111 |
| DESCRIPTION | - LIU T et al., Exp Mol Pathol., (20110000), vol. 91, pages 745 - 752 |
| DESCRIPTION | - MALECKI M. et al., J Stem Cell Res Ther, (20120000), vol. 2, page 5 |
| DESCRIPTION | - MALECKI M. et al., J Stem Cell Res Ther, (20130000), vol. 3, page 134 |
| DESCRIPTION | - MARTINEZ-RAMIREZ A et al., Cancer Genet Cytogenet., (20030000), vol. 141, pages 138 - 142 |
| DESCRIPTION | - MUZYCZKA et al., Current Topics in Microbiology and Immunology, (19920000), vol. 158, pages 97 - 129 |
| DESCRIPTION | - NICKLIN; BAKER, Curr. Gene Ther., (20020000), vol. 2, pages 273 - 293 |
| DESCRIPTION | - PEGRAM M et al., Oncogene, (19990000), vol. 18, pages 2241 - 2251 |
| DESCRIPTION | - POLO et al., Proc Natl Acad Sci USA, (19990000), vol. 96, pages 4598 - 4603 |
| DESCRIPTION | - QIU Y et al., Cancer Lett., (20120000), vol. 316, pages 31 - 38 |
| DESCRIPTION | - Remrnington's Pharmaceutical Sciences, Meade Publishing Co. |
| DESCRIPTION | - RUTLEDGE et al., J. Virol., (19980000), vol. 72, pages 309 - 319 |
| DESCRIPTION | - SAMULSKI et al., Proc. Natl. Acad. Sci. USA, (19820000), vol. 79, pages 2077 - 2081 |
| DESCRIPTION | - SHEN et al., Mol. Therapy, (20070000), vol. 15, no. 11, pages 1955 - 1962 |
| DESCRIPTION | - S. MURAMATSU et al., Virol., (19960000), vol. 221, pages 208 - 217 |
| DESCRIPTION | - SPIRIDON CI et al., Clin Cancer Res., (20020000), vol. 8, pages 1720 - 1730 |
| DESCRIPTION | - SYED et al., Am J Physiol Endocrinol Metab, (20130000), vol. 305, pages E1319 - E1326 |
| DESCRIPTION | - TORRES MP et al., Curr Pharm Des, (20120000), vol. 18, no. 17, pages 2472 - 2481 |
| DESCRIPTION | - UHLEN et al., Nat. Biotech., (20100000), vol. 28, pages 1248 - 1250 |
| DESCRIPTION | - VEGGIANI et al., Trends Biotechnol, (20140000), vol. 32, page 506 |
| DESCRIPTION | - VEGGIANI, PNAS, (20160000), vol. 113, pages 1202 - 1207 |
| DESCRIPTION | - VERHEIJI; ROTTIER, Advances Virol, (20120000), vol. 2012, pages 1 - 15 |
| DESCRIPTION | - WANG et al., Cancer Gene Therapy, (20100000), vol. 17, pages 559 - 570 |
| DESCRIPTION | - WARRINGTON et al., J. Virol., (20040000), vol. 78, page 6595 |
| DESCRIPTION | - WU et al., J. Virol., (20000000), vol. 74, pages 8635 - 8647 |
| DESCRIPTION | - ZAKEIR; HOWARTH, J. Am. Chem. Soc., (20100000), vol. 132, pages 4526 - 4527 |
| DESCRIPTION | - ZAKERI et al., PNAS, (20120000), vol. 109, pages E690 - E697 |
| DESCRIPTION | - ZAROGOULIDIS P. et al., J. Genet. Syndr. Gene Ther., (20130000), vol. 4, page 16849 |
| DESCRIPTION | - ZHANG SS et al., BMC Med., (20120000), vol. 10, page 85 |
| DESCRIPTION | - BELL, C. L.; GURDA, B. L.; VAN VLIET, K.; AGBANDJE-MCKENNA, M.; WILSON, J. M., "Identification of the galactose binding domain of the adeno-associated virus serotype 9 capsid", Journal of Virology, (20120000), vol. 86, no. 13, doi:doi:10.1128/JVI.00448-12, pages 7326 - 7333, XP055165759 |
| INTERNATIONAL-SEARCH-REPORT | - CHAMOUN-EMANUELLI A.M. ET AL., "In vitro incorporation of a cell-binding protein to alentiviral vector using an engineered split intein enables targeted delivery of genetic cargo.", BIOTECH. BIOENGIN., (20150812), vol. 112, no. 12, pages 2611 - 2617+sup, XP002785101 [X] 1,4,5,29,33,34,37-43,45-47,50,57,70-72 * the whole document * [I] 6,7,15,36,44,48,49,63-68 |
| INTERNATIONAL-SEARCH-REPORT | - CHEN Z.C., KASARANENI N. & CHAMOUN-EMANUELLI A.M., "Stable in vitro reprogramming of lentiviral vectors for target delivery of genetic cargo", MOL. THERAPY, (201605), vol. 24, no. S1, page S239, XP002785100 [X] 1,2,4,29,63-68,70-72 * abstract * [I] 5-7,15,36,39-41 |
| INTERNATIONAL-SEARCH-REPORT | - KASHENTSEVA E A ET AL, "Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, (20020115), vol. 62, no. 2, ISSN 0008-5472, pages 609 - 616, XP002227912 [I] 58 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - KEEBLE A.H. ET AL., "Evolving accelerated amidation by SpyTag/SpyCatcher to analyze membrane dynamics", ANGEW. CHEM. INT. ED., (201712), vol. 56, pages 16521 - 16525, XP002785104 [AP] 14,22 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - RIED M.U. ET AL., "Adeno-Associated Virus Capsids Displaying Immunoglobulin-Binding Domains Permit Antibody-Mediated Vector Retargeting to Specific Cell Surface Receptors", J. VIROL., (200205), vol. 76, no. 9, pages 4559 - 4566, XP002785103 [X] 1,4,10-12,24,29,33,37-43,45-47,50,56,57,63-68,70-72 * the whole document * [Y] 25-27 [I] 5-7,13,48,49 |
| INTERNATIONAL-SEARCH-REPORT | - SYED S.K. ET AL., "Ectonucleotidase NDPDase3 is abundant in pancreatic beta-cells and regulates glucose induced insulin secretion.", AM. J. ENDOCRINOL. METAB., (2013), vol. 305, pages E1319 - E1326, XP002787496 [I] 32,62 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - XIE H., NOTKINS A.L. & LAN M.S., "IA-2, a Transmembrane Protein Tyrosine Phosphatase, Is Expressed in HumanLung Cancer Cell Lines with Neuroendocrine Phenotype", CANCER RES., (19960615), vol. 56, pages 2742 - 2744, XP002787498 [I] 54 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - SANTIAGO-ORTIZ JORGE L ET AL, "Adeno-associated virus (AAV) vectors in cancer gene therapy", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, (20160112), vol. 240, doi:10.1016/J.JCONREL.2016.01.001, ISSN 0168-3659, pages 287 - 301, XP029759411 [A] 10-13 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - VEGGIANI G , ZAKERI B. & HOWARTH M., "Superglue from bacteria: unbreakable bridges for protein nanotechnology", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, (20140826), vol. 32, no. 10, doi:10.1016/J.TIBTECH.2014.08.001, ISSN 0167-7799, pages 506 - 512, XP029064532 [Y] 25-27 * the whole document * [A] 14,16-19,21 |
| INTERNATIONAL-SEARCH-REPORT | - BUCHEIT A.D. ET AL., "An Oncolytic Measles Virus Engineered to Enter CellsThrough the CD20 Antigen", MOL. THER., (200301), vol. 7, no. 1, pages 62 - 72, XP002787497 [I] 59 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - MÜNCH R.C. ET AL., "Displaying high-affinity ligands on adeno-associated viral vectors enables tumor cell-specific and safe gene transfer.", MOL. THERAPY, (201301), vol. 21, no. 1, pages 109 - 118+sup, XP002785102 [X] 1,5,8-12,23,29,33-35,37,38,40,41,43,45-48,57,70-72 * the whole document * [I] 13,36,39,42,44,49,50,63-69 |
| INTERNATIONAL-SEARCH-REPORT | - LIMIN CAO ET AL, "Characterization of a single-chain variable fragment (scFv) antibody directed against the human asialoglycoprotein receptor", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, ACADEMIC PRESS, US, vol. 44, no. 2, doi:10.1042/BA20050081, ISSN 0885-4513, (20060501), pages 65 - 72, (20101223), XP002643344 [I] 30,51 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - GIANLUCA VEGGIANI ET AL, "Programmable polyproteams built using twin peptide superglues", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, US, (20160119), vol. 113, no. 5, doi:10.1073/pnas.1519214113, ISSN 0027-8424, pages 1202 - 1207, XP055295991 [A] 14,20 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - WICKHAM T J ET AL, "TARGETED ADENOVIRUS-MEDIATED GENE DELIVERY TO T CELLS VIA CD3", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (19970101), vol. 71, no. 10, ISSN 0022-538X, pages 7663 - 7669, XP002935954 [I] 53 * the whole document * |
| INTERNATIONAL-SEARCH-REPORT | - V. W. VAN BEUSECHEM ET AL, "Efficient and Selective Gene Transfer into Primary Human Brain Tumors by Using Single-Chain Antibody-Targeted Adenoviral Vectors with Native Tropism Abolished", JOURNAL OF VIROLOGY, (20020315), vol. 76, no. 6, doi:10.1128/JVI.76.6.2753-2762.2002, ISSN 0022-538X, pages 2753 - 2762, XP055004358 [X] 1,4,8,29,33-35,37,38,40-43,45-47,57,63-72 * the whole document * [I] 35,48-50 |
| INTERNATIONAL-SEARCH-REPORT | - KASARANENI N. ET AL., "Retargeting lentiviruses via spycather-spytag chemistry for gene delivery into specific cell types.", MBIO, (20171212), vol. 8, no. 6, pages E01860 - 17, XP002785105 [XP] 1-8,14-17,24-26,33-41,44-50,57,63-65,70,72 * the whole document * [I] 9-13,18-23,42,43,66-69,71 |
| INTERNATIONAL-SEARCH-REPORT | - MIHARU KOBAYASHI ET AL, "Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200", JOURNAL OF TRANSLATIONAL MEDICINE, BIOMED CENTRAL, (20140106), vol. 12, no. 1, doi:10.1186/1479-5876-12-4, ISSN 1479-5876, XP021174598 [I] 31,61 * the whole document * |
| OPPOSITION | - Anonymous , "Chain B, Minimized B-domain of Protein A Z34C", Protein, NCBI, XP093149022 |
| OPPOSITION | - Anonymous, "Cross-Linking Reagents Technical Handbook", Cross-Linking Reagents Technical Handbook, Pierce Biotechnology, Inc., (20050101), pages 1 - 48, XP009559150 |
| OPPOSITION | - Anonymous, "Mini-review: The T Cell Marker, CD3 Antigen and Antibodies", Bio-Rad - Research Areas - Immunology - Immunology Resources, (20160101), pages 1 - 5, XP093149052 |
| OPPOSITION | - Anonymous, "Virus-like particle", Wikipedia, (20170420), pages 1 - 5, Wikipedia, URL: https://en.wikipedia.org/w/index.php?title=Virus-like_particle&oldid=776342056, (20240408), XP093149025 |
| OPPOSITION | - D90: Statement of Professor Mark A. Kay, M.D., Ph.D. |
| OPPOSITION | - Elena A. Kashentseva; Toshiro Seki; David T. Curiel; Igor P. Dmitriev, "Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain.", Cancer research, American Association for Cancer Research, US, US, (20020115), vol. 62, no. 2, ISSN 0008-5472, pages 609 - 616, XP002227912 |
| OPPOSITION | - Hong Xie; Abner L. Notkins; Michael S. Lan, "IA-2, a Transmembrane Protein Tyrosine Phosphatase, Is Expressed in HumanLung Cancer Cell Lines with Neuroendocrine Phenotype", Cancer research, American Association for Cancer Research, US, US, (19960615), vol. 56, no. 12, ISSN 0008-5472, pages 2742 - 2744, XP002787498 |
| OPPOSITION | - Inchan Kwon ; David V. Schaffer, "Designer Gene Delivery Vectors: Molecular Engineering and Evolution of Adeno-Associated Viral Vectors for Enhanced Gene Transfer", Pharmaceutical Research, NL , (20070901), vol. 25, no. 3, doi:10.1007/s11095-007-9431-0, ISSN 1573-904X, pages 489 - 499, XP019579477 |
| OPPOSITION | - Kasaraneni, Nagarjun; Emanuelli, Ana M Chamoun; Wright, Gus; Smith, Roger; Chen, Zhilei, "Versatile Retargeting Lentiviral System bearing the Isopeptide Bond Pair SpyTag-SpyCatcher", 20th Annual Student Research Week, March 27-31, 2017, Abstract Book, (20170101), pages 282 - 283, XP009553291 |
| OPPOSITION | - Mihic John S., R. Adron Harris, "GABA and the GABAA Receptor ", Alcohol health and research world, (19970101), vol. 21, no. 2, ISSN 0090-838X, pages 127 - 131, XP093149249 |
| OPPOSITION | - Ojala David Stephen, "Improved Strategies for Directed Evolution of Adeno-Associated Virus Gene Therapy Vectors", Dissertation, UC Berkeley., (20170101), pages 1 - 115, Dissertation, URL: https://escholarship.org/content/qt9p95c246/qt9p95c246.pdf?t=pwzt59, (20240411), XP093150771 |
| OPPOSITION | - Tai, W. ; Mahato, R. ; Cheng, K., "The role of HER2 in cancer therapy and targeted drug delivery", Journal of Controlled Release, Elsevier, AMSTERDAM, NL, AMSTERDAM, NL , (20100915), vol. 146, no. 3, ISSN 0168-3659, pages 264 - 275, XP027260357 |
| OPPOSITION | - Van Vliet Kim M; Blouin Veronique; Brument Nicole; Agbandje-McKenna Mavis; Snyder Richard O, "The role of the adeno-associated virus capsid in gene transfer", Antibody-drug conjugates, Humana Press, US, US , (20080101), vol. 437, ISBN 978-1-62703-541-5, pages 51 - 91, XP009127443 |
| OPPOSITION | - Simone Jeger; Kurt Zimmermann; Alain Blanc; Jürgen Grünberg; Michael Honer; Peter Hunziker; Harriet Struthers; Roger Schibli, "Site‐Specific and Stoichiometric Modification of Antibodies by Bacterial Transglutaminase", Angewandte Chemie International Edition, Hoboken, USA, (20101125), vol. 49, no. 51, doi:10.1002/anie.201004243, ISSN 1433-7851, pages 9995 - 9997, XP072081099 |
| OPPOSITION | - Anthony H. Keeble; Anusuya Banerjee; Matteo P. Ferla; Samuel C. Reddington; Irsyad N. A. Khairil Anuar; Mark Howarth, "Evolving Accelerated Amidation by SpyTag/SpyCatcher to Analyze Membrane Dynamics", Angewandte Chemie International Edition, Verlag Chemie, Hoboken, USA, Hoboken, USA, (20171205), vol. 56, no. 52, doi:10.1002/anie.201707623, ISSN 1433-7851, pages 16521 - 16525, XP072090983 |
| OPPOSITION | - Hildegard Büning; Luca Perabo; Oliver Coutelle; Sibille Quadt‐humme; Michael Hallek, "Recent developments in adeno‐associated virus vector technology", The Journal of Gene Medicine, US , (20080701), vol. 10, no. 7, doi:10.1002/jgm.1205, ISSN 1099-498X, pages 717 - 733, XP055449844 |
| OPPOSITION | - Min Liang, Pariente Nonia, Morizono Kouki, Chen Irvin S. Y., "Targeted transduction of CD34+ hematopoietic progenitor cells in nonpurified human mobilized peripheral blood mononuclear cells", The Journal of Gene Medicine, John Wiley & Sons, Inc, US, US , (20090301), vol. 11, no. 3, doi:10.1002/jgm.1290, ISSN 1099-498X, pages 185 - 196, XP055122101 |
| OPPOSITION | - Yarong Liu, Yun Fang, Yu Zhou, Ebrahim Zandi, Chi-Lin Lee, Kye-Il Joo, Pin Wang, "Site-Specific Modification of Adeno-Associated Viruses via a Genetically Engineered Aldehyde Tag", Small, Wiley, Hoboken, USA, Hoboken, USA, (20130211), vol. 9, no. 3, doi:10.1002/smll.201201661, ISSN 1613-6810, pages 421 - 429, XP055421753 |
| OPPOSITION | - Rabinowitz Joseph E., Samulski R.Jude, "The Adeno-Associated Virus Crystal: Impact Inversely Proportional to Size", Molecular Therapy, US , (20021001), vol. 6, no. 4, doi:10.1006/mthe.2002.0704, ISSN 1525-0016, pages 443 - 445, XP093195787 |
| OPPOSITION | - Castle Michael J., Turunen Heikki T., Vandenberghe Luk H., Wolfe John H., "Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids", Castle Michael J., Turunen Heikki T., Vandenberghe Luk H., Wolfe John H., Waleed M. Hussein, Mariusz Skwarczynski, Istvan Toth, Peptide Synthesis- Methods and Protocols, New York, NY, Springer New York, (20160101), vol. 1382, pages 133 - 149, doi:10.1007/978-1-4939-3271-9_10, ISBN 978-1-0716-0229-4, XP055944095 |
| OPPOSITION | - Michael F. Naso et al, "Adeno-Associated Virus (AAV) as a Vector for Gene Therapy", BIODRUGS, Adis International Ltd., NZ, NZ , (20170801), vol. 31, no. 4, doi:10.1007/s40259-017-0234-5, ISSN 1173-8804, pages 317 - 334, XP055547503 |
| OPPOSITION | - Chuanling Zhang et al, "Development of next generation adeno-associated viral vectors capable of selective tropism and efficient gene delivery", Biomaterials, Elsevier, AMSTERDAM, NL, AMSTERDAM, NL , (20160201), vol. 80, doi:10.1016/j.biomaterials.2015.11.066, ISSN 0142-9612, pages 134 - 145, XP055727141 |
| OPPOSITION | - Reddington Samuel C; Howarth Mark, "Secrets of a covalent interaction for biomaterials and biotechnology: SpyTag and SpyCatcher", CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, GB , (20151030), vol. 29, doi:10.1016/j.cbpa.2015.10.002, ISSN 1367-5931, pages 94 - 99, XP029342251 |
| OPPOSITION | - Dawidczyk Charlene M. et al, "State-of-the-art in design rules for drug delivery platforms: Lessons learned from FDA-approved nanomedicines", Journal of Controlled Release, Elsevier, NL, NL , (20140527), vol. 187, doi:10.1016/j.jconrel.2014.05.036, ISSN 0168-3659, pages 133 - 144, XP028860098 |
| OPPOSITION | - Santiago-Ortiz Jorge L.; Schaffer David V., "Adeno-associated virus (AAV) vectors in cancer gene therapy", Journal of Controlled Release, Elsevier, AMSTERDAM, NL, AMSTERDAM, NL , (20160112), vol. 240, doi:10.1016/j.jconrel.2016.01.001, ISSN 0168-3659, pages 287 - 301, XP029759411 |
| OPPOSITION | - Veggiani Gianluca; Zakeri Bijan; Howarth Mark, "Superglue from bacteria: unbreakable bridges for protein nanotechnology", TRENDS IN BIOTECHNOLOGY., ELSEVIER PUBLICATIONS, CAMBRIDGE., GB, GB , (20140826), vol. 32, no. 10, doi:10.1016/j.tibtech.2014.08.001, ISSN 0167-7799, pages 506 - 512, XP029064532 |
| OPPOSITION | - Gigout, L. Rebollo, P. Clement, N. Warrington, K.H. Muzyczka, N. Linden, R.M. Weber, T., "Altering AAV tropism with mosaic viral capsids", Molecular Therapy, Elsevier Inc., US, US , (20050601), vol. 11, no. 6, doi:10.1016/j.ymthe.2005.03.005, ISSN 1525-0016, pages 856 - 865, XP005002705 |
| OPPOSITION | - Wu, Z. Asokan, A. Samulski, R.J., "Adeno-associated Virus Serotypes: Vector Toolkit for Human Gene Therapy", Molecular Therapy, Elsevier Inc., US, US , (20060812), vol. 14, no. 3, doi:10.1016/j.ymthe.2006.05.009, ISSN 1525-0016, pages 316 - 327, XP005844824 |
| OPPOSITION | - Amanda D Bucheit, Shaji Kumar, Deanna M Grote, Yukang Lin, Veronika von Messling, Roberto B Cattaneo, Adele K Fielding, "An Oncolytic Measles Virus Engineered to Enter Cells Through the CD20 Antigen", Molecular Therapy, Elsevier Inc., US, US , (20030101), vol. 7, no. 1, doi:10.1016/s1525-0016(02)00033-3, ISSN 1525-0016, pages 62 - 72, XP002787497 |
| OPPOSITION | - Girod A; Ried M; Wobus C; Lahm H; Leike K; Kleinschmidt J; Deleage G; Hallek M, "GENETIC CAPSID MODIFICATIONS ALLOW EFFICIENT RE-TARGETING OF ADENO-ASSOCIATED VIRUS TYPE 2", Nature Medicine, Nature Publishing Group US, New York, New York, (19990901), vol. 5, no. 9, doi:10.1038/12491, ISSN 1078-8956, pages 1052 - 1056, XP002128040 |
| OPPOSITION | - Yu C-Y; Yuan Z; Cao Z; Wang B; Qiao C; Li J; Xiao X, "A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery", Gene Therapy, Nature Publishing Group, London, GB, GB , (20090528), vol. 16, no. 8, doi:10.1038/gt.2009.59, ISSN 0969-7128, pages 953 - 962, XP037771311 |
| OPPOSITION | - M Nonnenmacher, T Weber, "Intracellular transport of recombinant adeno-associated virus vectors", Gene Therapy, Nature Publishing Group, London, GB, GB , (20120601), vol. 19, no. 6, doi:10.1038/gt.2012.6, ISSN 0969-7128, pages 649 - 658, XP055222632 |
| OPPOSITION | - Matthew D Stachler, Irwin Chen, Alice Y Ting, Jeffrey S Bartlett, "Site-specific Modification of AAV Vector Particles With Biophysical Probes and Targeting Ligands Using Biotin Ligase", Molecular Therapy, No longer published by Elsevier, (20080801), vol. 16, no. 8, doi:10.1038/mt.2008.129, ISSN 15250016, pages 1467 - 1473, XP055187899 |
| OPPOSITION | - MÜNCH R.C. ET AL., "Displaying high-affinity ligands on adeno-associated viral vectors enables tumor cell-specific and safe gene transfer.", MOL. THERAPY, (20130101), vol. 21, no. 1, pages 109 - 118+sup, XP002785102 |
| OPPOSITION | - Summerford Candace, Samulski R. Jude, "AAVR: A Multi-Serotype Receptor for AAV", Molecular Therapy, Elsevier Inc, United States, United States, (20160401), vol. 24, no. 4, doi:10.1038/mt.2016.49, ISSN 1525-0016, pages 663 - 666, XP055830059 |
| OPPOSITION | - S. Pillay et al, "An essential receptor for adeno-associated virus infection", Nature, vol. 530, no. 7588, doi:10.1038/nature16465, pages 108 - 112, XP055384253 |
| OPPOSITION | - Deverman Benjamin E, Pravdo Piers L, Simpson Bryan P, Kumar Sripriya Ravindra, Chan Ken Y, Banerjee Abhik, Wu Wei-Li, Yang Bin, Huber Nina, Pasca Sergiu P, Gradinaru Viviana, "Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain", Nature Biotechnology, New York, (20160201), vol. 34, no. 2, doi:10.1038/nbt.3440, ISSN 1087-0156, pages 1 - 21, XP093195776 |
| OPPOSITION | - Loiler S A; Conlon T J; Song S; Tang Q; Warrington K H; Agarwal A; Kapturczak M; Li C; Ricordi C; Atkinson M A; Muzyczka N; Flotte T R, "Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver", Gene Therapy, Nature Publishing Group, London, GB, GB , (20030808), vol. 10, no. 18, doi:10.1038/sj.gt.3302046, ISSN 0969-7128, pages 1551 - 1558, XP037772301 |
| OPPOSITION | - SHEN XUAN, STORM T, KAY M A, "Characterization of the relationship of AAV capsid domain swapping to liver transduction efficiency.", Molecular Therapy, Elsevier Inc., US, US , (20071101), vol. 15, no. 11, doi:10.1038/sj.mt.6300293, ISSN 1525-0016, pages 1955 - 1962, XP002595612 |
| OPPOSITION | - Zhida Liu, Zhou Hang, Wang Wenjun, Tan Wenjie, Fu Yang-Xin, Zhu Mingzhao, "A novel method for synthetic vaccine construction based on protein assembly", Scientific Reports, (20141201), vol. 4, no. 1, doi:10.1038/srep07266, page 7266, XP055616112 |
| OPPOSITION | - Karl D. Brune, Darren B. Leneghan, Iona J. Brian, Andrew S. Ishizuka, Martin F. Bachmann, Simon J. Draper, Sumi Biswas, Mark Howarth, "Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization", Scientific Reports, vol. 6, doi:10.1038/srep19234, page 19234, XP055258597 |
| OPPOSITION | - Liu Ke, Lei Run, Li Qiong, Wang Xin-Xin, Wu Qian, An Peng, Zhang Jianchao, Zhu Minyan, Xu Zhiheng, Hong Yang, Wang Fudi, Shen Ying, Li Hongchang, Li Huashun, "Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity", Scientific Reports, Nature Publishing Group, US, US , (20160216), vol. 6, no. 1, doi:10.1038/srep21019, ISSN 2045-2322, pages 21019 - 14, XP093149246 |
| OPPOSITION | - Vanessa Siegmund, Birgit Piater, Bijan Zakeri, Thomas Eichhorn, Frank Fischer, Carl Deutsch, Stefan Becker, Lars Toleikis, Björn Hock, Ulrich A. K. Betz, Harald Kolmar, "Spontaneous Isopeptide Bond Formation as a Powerful Tool for Engineering Site-Specific Antibody-Drug Conjugates", Scientific Reports, Nature Publishing Group, US, US , (20161201), vol. 6, no. 1, doi:10.1038/srep39291, ISSN 2045-2322, pages 39291 - 9, XP055606471 |
| OPPOSITION | - NGUYEN R, HUC I, "Optimizing the reversibility of hydrazone formation for dynamic combinatorial chemistry.", Chemical Communications, Royal Society of Chemistry, UK, UK , (20030421), no. 8, doi:10.1039/b211645f, ISSN 1359-7345, pages 942 - 943, XP002265250 |
| OPPOSITION | - Limin Cao; Guanxin Shen; Yinchang Zhu; Weiyu Wang; Xiaorong Zhao; Qing Ye; Huifen Zhu; Zhixian Lu; Jin Si, "Characterization of a single‐chain variable fragment (scFv) antibody directed against the human asialoglycoprotein receptor", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, ACADEMIC PRESS, US, US , (20101223), vol. 44, no. 2, doi:10.1042/BA20050081, ISSN 0885-4513, pages 65 - 72, XP071712726 |
| OPPOSITION | - Toshie Sakuma; Michael a Barry; Yasuhiro Ikeda, "Lentiviral vectors: basic to translational", Biochemical Journal, GB , (20120501), vol. 443, no. 3, doi:10.1042/BJ20120146, ISSN 0264-6021, pages 603 - 618, XP055258613 |
| OPPOSITION | - B. Zakeri, Jacob O Fierer, Emrah Celik, Emily C Chittock, Ulrich Schwarz-Linek, Vincent T Moy, Mark Howarth, James A Wells, "Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20120320), vol. 109, no. 12, doi:10.1073/pnas.1115485109, ISSN 00278424, pages E690 - E697, XP055217264 |
| OPPOSITION | - Christopher M. Koth, Jeremy M. Murray, Susmith Mukund, Azadeh Madjidi, Alexandra Minn, Holly J. Clarke, Terence Wong, Vicki Chiang, Elizabeth Luis, Alberto Estevez, Jesus Rondon, Yingnan Zhang, Isidro Hötzel, and Bernard B. Allan, "Molecular basis for negative regulation of the glucagon receptor.", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20120904), vol. 109, no. 36, doi:10.1073/PNAS.1206734109, ISSN 0027-8424, pages 14393 - 14398, XP002693278 |
| OPPOSITION | - Jacob O. Fierer, Gianluca Veggiani, Mark Howarth, "SpyLigase peptide–peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20140401), vol. 111, no. 13, doi:10.1073/pnas.1315776111, ISSN 0027-8424, pages E1176 - E1181, XP055296264 |
| OPPOSITION | - Gianluca Veggiani, Tomohiko Nakamura, Michael D. Brenner, Raphaël V. Gayet, Jun Yan, Carol V. Robinson, Mark Howarth, "Programmable polyproteams built using twin peptide superglues", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20160202), vol. 113, no. 5, doi:10.1073/pnas.1519214113, ISSN 0027-8424, pages 1202 - 1207, XP055295991 |
| OPPOSITION | - Liu Zhida, Zhou Hang, Wang Wenjun, Fu Yang-Xin, Zhu Mingzhao, "A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice", OncoImmunology, (20160602), vol. 5, no. 6, doi:10.1080/2162402X.2016.1147641, ISSN 2162-402X, pages e1147641 - 9, XP093149003 |
| OPPOSITION | - Hastie Eric, Samulski R. Jude, "Adeno-Associated Virus at 50: A Golden Anniversary of Discovery, Research, and Gene Therapy Success—A Personal Perspective", HUMAN GENE THERAPY, Mary Ann Liebert, Inc. Publishers, GB, GB , (20150501), vol. 26, no. 5, doi:10.1089/hum.2015.025, ISSN 1043-0342, pages 257 - 265, XP093149033 |
| OPPOSITION | - Sonntag Florian et al, "Adeno-Associated Virus Type 2 Capsids with Externalized VP1/VP2 Trafficking Domains Are Generated prior to Passage through the Cytoplasm and Are Maintained until Uncoating Occurs in the Nucleus", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (20061101), vol. 80, no. 22, doi:10.1128/JVI.01056-06, ISSN 0022-538X, pages 11040 - 11054, XP093269629 |
| OPPOSITION | - Pulmanausahakul Rojjanaporn, Li Jianwei, Schnell Matthias J., Dietzschold Bernhard, "The Glycoprotein and the Matrix Protein of Rabies Virus Affect Pathogenicity by Regulating Viral Replication and Facilitating Cell-to-Cell Spread", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (20080301), vol. 82, no. 5, doi:10.1128/JVI.02327-07, ISSN 0022-538X, pages 2330 - 2338, XP093149064 |
| OPPOSITION | - T J Wickham, G M Lee, J A Titus, G Sconocchia, T Bakács, I Kovesdi, D M Segal, "TARGETED ADENOVIRUS-MEDIATED GENE DELIVERY TO T CELLS VIA CD3", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (19971001), vol. 71, no. 10, doi:10.1128/jvi.71.10.7663-7669.1997, ISSN 0022-538X, pages 7663 - 7669, XP002935954 |
| OPPOSITION | - P. Wu, Xiao W., Conlon T., Hughes J., Agbandje-Mckenna M., Ferkol T., Flotte T., Muzyczka N., "Mutational Analysis of the Adeno-Associated Virus Type 2 (AAV2) Capsid Gene and Construction of AAV2 Vectors with Altered Tropism", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (20000915), vol. 74, no. 18, doi:10.1128/JVI.74.18.8635-8647.2000, ISSN 0022-538X, pages 8635 - 8647, XP055548655 |
| OPPOSITION | - V. W. Van Beusechem, J. Grill, D. C. J. Mastenbroek, T. J. Wickham, P. W. Roelvink, H. J. Haisma, M. L. M. Lamfers, C. M. F. Dirven, H. M. Pinedo, W. R. Gerritsen, "Efficient and Selective Gene Transfer into Primary Human Brain Tumors by Using Single-Chain Antibody-Targeted Adenoviral Vectors with Native Tropism Abolished", Journal of Virology, American Society for Microbiology., (20020315), vol. 76, no. 6, doi:10.1128/JVI.76.6.2753-2762.2002, ISSN 0022538X, pages 2753 - 2762, XP055004358 |
| OPPOSITION | - M. U. Ried, A. Girod, K. Leike, H. Buning, M. Hallek, "Adeno-Associated Virus Capsids Displaying Immunoglobulin-Binding Domains Permit Antibody-Mediated Vector Retargeting to Specific Cell Surface Receptors", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (20020501), vol. 76, no. 9, doi:10.1128/JVI.76.9.4559-4566.2002, ISSN 0022-538X, pages 4559 - 4566, XP055353693 |
| OPPOSITION | - THOMAS C E,ET AL, "Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors.", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (20040301), vol. 78, no. 6, doi:10.1128/JVI.78.6.3110-3122.2004, ISSN 0022-538X, pages 3110 - 3122, XP002312778 |
| OPPOSITION | - Nagarjun Kasaraneni, Ana M. Chamoun-Emanuelli, Gus Wright, Zhilei Chen, "Retargeting Lentiviruses via SpyCatcherSpyTag Chemistry for Gene Delivery into Specific Cell Types", mBio, American Society for Microbiology, US, US , (20171217), vol. 8, no. 6, doi:10.1128/mBio .01860-17, ISSN 2150-7511, pages e01860 - 17, XP055704891 |
| OPPOSITION | - Syed Samreen K., Kauffman Audra L., Beavers Lisa S., Alston James T., Farb Thomas B., Ficorilli James, Marcelo Marialuisa C., Brenner Martin B., Bokvist Krister, Barrett David G., Efanov Alexander M., "Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion", AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM., AMERICAN PHYSIOLOGICAL SOCIETY, BETHESDA, MD., US, US , (20131115), vol. 305, no. 10, doi:10.1152/ajpendo.00328.2013, ISSN 0193-1849, pages E1319 - E1326, XP093149043 |
| OPPOSITION | - Harris Rebecca Louise, Van Den Berg Carmen Wilma, Bowen Derrick John, "ASGR1 and ASGR2 , the Genes that Encode the Asialoglycoprotein Receptor (Ashwell Receptor), Are Expressed in Peripheral Blood Monocytes and Show Interindividual Differences in Transcript Profile", Molecular Biology International, Sage - Hindawi Access to Research, (20120802), vol. 2012, doi:10.1155/2012/283974, ISSN 2090-2182, pages 283974 - 10, XP093149040 |
| OPPOSITION | - M. H. Verheije, P. J. M. Rottier, "Retargeting of Viruses to Generate Oncolytic Agents", Advances in Virology, Hindawi Publishing Corporation, US, US , (20120101), vol. 2012, doi:10.1155/2012/798526, ISSN 1687-8639, pages 1 - 15, XP055574134 |
| OPPOSITION | - L. M. Draper, M. L. M. Kwong, A. Gros, S. Stevanovi , E. Tran, S. Kerkar, M. Raffeld, S. A. Rosenberg, C. S. Hinrichs, "Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6", Clinical Cancer Research, Association for Cancer Research, US, US, (20151001), vol. 21, no. 19, doi:10.1158/1078-0432.CCR-14-3341, ISSN 1078-0432, pages 4431 - 4439, XP055437983 |
| OPPOSITION | - Takawale Abhijit, Zhang Pu, Patel Vaibhav B., Wang Xiuhua, Oudit Gavin, Kassiri Zamaneh, "Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin β1 Interaction", Hypertension, Lippincott Williams & Wilkins, US, US , (20170601), vol. 69, no. 6, doi:10.1161/HYPERTENSIONAHA.117.09045, ISSN 0194-911X, pages 1092 - 1103, XP093149245 |
| OPPOSITION | - Miharu Kobayashi;Carlos Salomon;Jorge Tapia;Sebastian E Illanes;Murray D Mitchell;Gregory E Rice, "Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200", Journal of Translational Medicine, BioMed Central, (20140106), vol. 12, no. 1, doi:10.1186/1479-5876-12-4, ISSN 1479-5876, page 4, XP021174598 |
| OPPOSITION | - Susan Thrane, Janitzek Christoph M., Matondo Sungwa, Resende Mafalda, Gustavsson Tobias, De Jongh Willem Adriaan, Clemmensen Stine, Roeffen Will, Van De Vegte‑bolmer Marga, Van Gemert Geert Jan, Sauerwein Robert, Schiller John T., Nielsen Morten A., Theander Thor G., Salanti Ali, Sander Adam F., "Bacterial superglue enables easy development of efficient virus-like particle based vaccines", Journal of Nanobiotechnology, (20160101), vol. 14, no. 30, doi:10.1186/s12951-016-0181-1, pages 1 - 16, XP055379624 |
| OPPOSITION | - Lai Bi-Qin, Qiu Xue-Chen, Zhang Ke, Zhang Rong-Yi, Jin Hui, Li Ge, Shen Hui-Yong, Wu Jin-Lang, Ling Eng-Ang, Zeng Yuan-Shan, "Cholera Toxin B Subunit Shows Transneuronal Tracing after Injection in an Injured Sciatic Nerve", PLOS ONE, Public Library of Science, US, US , (20151207), vol. 10, no. 12, doi:10.1371/journal.pone.0144030, ISSN 1932-6203, page e0144030, XP093149069 |
| OPPOSITION | - CHOI VIVIAN W, MCCARTY DOUGLAS M, SAMULSKI JUDE R, "AAV hybrid serotypes: Improved vectors for gene delivery", Current Gene Therapy, Bentham Science Publishers Ltd., NL, NL , (20050601), vol. 5, no. 3, doi:10.2174/1566523054064968, ISSN 1566-5232, pages 299 - 310, XP002462124 |
| OPPOSITION | - Balakrishnan Balaji, Jayandharan Giridhara, "Basic Biology of Adeno-Associated Virus (AAV) Vectors Used in Gene Therapy", Current Gene Therapy, NL , (20140101), vol. 14, no. 2, doi:10.2174/1566523214666140302193709, ISSN 1566-5232, pages 1 - 15, XP093195782 |
| OPPOSITION | - Drouin Lauren M, Agbandje-Mckenna Mavis, "Adeno-Associated Virus Structural Biology as a Tool in Vector Development", Future Virology, UK , (20131201), vol. 8, no. 12, doi:10.2217/fvl.13.112, ISSN 1746-0794, pages 1 - 27, XP093195788 |
| OPPOSITION | - Worthen Christal A., Enns Caroline A., "The role of hepatic transferrin receptor 2 in the regulation of iron homeostasis in the body", Frontiers in pharmacology, Frontiers Research Foundation, CH, CH , (20140306), vol. 5, doi:10.3389/fphar.2014.00034, ISSN 1663-9812, pages 34 - 8, XP093149248 |
