Pharmaceutical Composition Containing Glycopyrrolate And A Beta2 Adrenoceptor Agonist

Patent No. EP2228064 (titled "Pharmaceutical Composition Containing Glycopyrrolate And A Beta2 Adrenoceptor Agonist") was filed by Novartis on May 17, 2005. The application was issued on Dec 11, 2019.

Patent Summary

A medicament for treating inflammatory or obstructive airways diseases comprises glycopyrrolate (A) and a compound of formula I (B), administered separately, together, simultaneously, sequentially, or separately. Compound (B) is in free, salt, or solvate form, where the substituent W is defined by specific parameters: $R^1=OH$; $R^2, R^3, R^4, R^7, R^8, R^9, R^{10}=H$; $R^x, R^y=-CH_2-$; and $R^5, R^6=CH_3CH_2-$. The medicament may include co-therapeutic agents (e.g., steroids, PDE4 inhibitors) and be formulated as a pharmaceutical composition, such as a dry powder in capsules, a multi-dose dry powder inhaler, or an aerosol for metered-dose inhalation. It is applicable to asthma (including "wheezy-infant syndrome"), COPD, cystic fibrosis, and pneumoconiosis. The invention further provides pharmaceutical kits and inhalation devices for delivering these components.

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Patent Oppositions (11)

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Dossier Documents

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  • Date

    Description

EP2228064

NOVARTIS
Application Number
EP10164976A
Filing Date
May 17, 2005
Status
Granted And Under Opposition
Nov 8, 2019
Publication Date
Dec 11, 2019