Method To Improve Virus Removal In Protein Purification

Patent No. EP2462158 (titled "Method To Improve Virus Removal In Protein Purification") was filed by F Hoffmann LA Roche on Aug 6, 2010. The application was issued on Jan 10, 2018.

Patent Summary

Improving the filtration capacity of virus filters during protein purification by using a prefiltration step before virus filtration. The prefiltration step involves subjecting the protein solution to a cation exchange step and an endotoxin removal step in any order. This prefiltration improves the virus filtration capacity compared to just cation exchange or endotoxin removal prior to virus filtration. The prefiltration steps can be done simultaneously in a single module.

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Patent Oppositions (11)

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Dossier Documents

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EP2462158

F HOFFMANN LA ROCHE
Application Number
EP10740823A
Filing Date
Aug 6, 2010
Status
Granted And Under Opposition
Dec 8, 2017
Publication Date
Jan 10, 2018