Subcutaneous Formulations Of Anti-Cd38 Antibodies And Their Uses

Patent No. EP3370770 (titled "Subcutaneous Formulations Of Anti-Cd38 Antibodies And Their Uses") was filed by Janssen Biotech on Nov 1, 2016. The application was issued on Jan 20, 2021.

Patent Summary

Subcutaneous injection of anti-CD38 antibodies for treating cancers like multiple myeloma, using a hyaluronidase enzyme to reduce viscosity and improve tissue penetration. The composition contains an anti-CD38 antibody at 20 mg/mL concentration and a hyaluronidase like rHuPH20 at 500 U/mL. The hyaluronidase helps the subcutaneous injection reach deeper tissues by breaking down hyaluronic acid in the extracellular matrix.

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Dossier Documents

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EP3370770

JANSSEN BIOTECH
Application Number
EP16862791A
Filing Date
Nov 1, 2016
Status
Revoked
Jan 22, 2025
Publication Date
Jan 20, 2021