Patent No. EP3689383 (titled "Chimeric Antigen Receptors Targeting B-Cell Maturation Antigen") was filed by The United States OF America on Mar 15, 2013. The application was issued on Dec 31, 2025.
A pharmaceutical composition comprising T-cells engineered to express a chimeric antigen receptor (CAR) that targets B-cell Maturation Antigen (BCMA) for the treatment of multiple myeloma. The CAR comprises an antigen recognition moiety directed against BCMA and a T-cell activation moiety that includes a transmembrane domain and an intracellular signaling domain. The composition is administered to patients with multiple myeloma to induce antigen-specific T-cell responses against BCMA-expressing cancer cells.
Latest UPC cases involving this patent.
| Case Number | Filing Date | Plaintiff | Proceeding Type |
|---|---|---|---|
| UPC_CFI_0000029/2026 | Jan 5, 2026 | 2Seventy BIO | Infringement |

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative |
|---|---|---|
| BOULT WADE TENNANT | Dec 31, 2025 | BOULT WADE TENNANT |
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