Formulations Of (+)-2-[1-(3-Ethoxy-4-Methoxy-Phenyl)-2-Methanesulfonyl-Ethyl]-4-Acetyl Aminoisoindoline-1,3-Dione

Patent No. EP3756650 (titled "Formulations Of (+)-2-[1-(3-Ethoxy-4-Methoxy-Phenyl)-2-Methanesulfonyl-Ethyl]-4-Acetyl Aminoisoindoline-1,3-Dione") was filed by Amgen Europe on Dec 26, 2012. The application was issued on Aug 20, 2025.

Patent Summary

Pharmaceutical compositions comprising (+)-2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-4-acetylaminoisoindoline-1,3-dione (Compound A) for treating various diseases and disorders, including cancer, pain, inflammatory diseases, and ocular neovascular diseases. The compositions comprise Compound A in combination with fillers, disintegrants, and lubricants, and may be formulated as tablets or capsules. The compositions exhibit advantageous physical and pharmacological properties, including fast disintegration, low friability, and stability.

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Dossier Documents

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EP3756650

AMGEN EUROPE
Application Number
EP20172615A
Filing Date
Dec 26, 2012
Status
Granted And Under Opposition
Jul 18, 2025
Publication Date
Aug 20, 2025