Patent No. EP4241767 (titled "Novel Lipids And Compositions For The Delivery Of Therapeutics") was filed by Arbutus Biopharma on Nov 10, 2009. The application was issued on Oct 23, 2024.
Lipid particles comprising cationic lipids that enhance the delivery of therapeutic nucleic acids, including siRNA and plasmids, to cells. The particles contain a cationic lipid that provides enhanced membrane fluidity, while the therapeutic agent is encapsulated within the lipid particle. The lipid particles exhibit improved therapeutic index compared to conventional nucleic acid delivery systems, with enhanced activity and reduced toxicity. The lipid particles can be formulated for systemic delivery, including intracellular targeting, and are suitable for a wide range of therapeutic applications, including gene therapy, RNAi, and immunostimulation.
Latest UPC cases involving this patent.
| Case Number | Filing Date | Plaintiff | Proceeding Type |
|---|---|---|---|
| UPC_CFI_607/2025 | Jul 8, 2025 | Moderna | Counter Claim For Revocation |
| UPC_CFI_192/2025 | Mar 3, 2025 | Arbutus Biopharma, Genevant Sciences | Infringement |

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative |
|---|---|---|
| ARROWHOUSE | Jul 23, 2025 | VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBB |
| KELTIE | Jul 23, 2025 | - |
| MERCK SHARP & DOHME UK | Jul 23, 2025 | COHAUSZ & FLORACK |
| MODERNA | Apr 29, 2025 | HOFFMANN EITLE |
The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
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