Patent No. US12112839 (titled "Data Based Cancer Research And Treatment Systems And Methods") was filed by Ares Capital Corp on Mar 22, 2023.
’839 is related to the field of data management and analysis in the context of cancer treatment . Specifically, it addresses the challenges of integrating diverse data types, including clinical records and genomic sequencing data, to improve cancer treatment planning and outcomes. The background acknowledges the increasing complexity of cancer treatment, the limitations of traditional methods, and the potential of genomic sequencing to personalize treatment strategies. However, it also recognizes the difficulties in managing and utilizing the vast amounts of data generated by genomic sequencing and other clinical information.
The underlying idea behind ’839 is to create a multi-database system that optimizes data storage and access for different purposes. This involves taking raw clinical and genomic data, structuring it, and then storing it in separate databases tailored for specific uses. The key insight is that a single database structure is not optimal for all tasks, and that separating data into purpose-built databases can improve efficiency and adaptability. This allows different applications and users to access the data in the most efficient format for their needs.
The claims of ’839 focus on a method and system for managing cancer patient data using multiple databases. The independent claims cover the steps of storing user application programs, obtaining clinical records and genomic sequencing data, shaping the genomic data, and then distributing this data into three separate databases: a first database for system structured data, a second database optimized for application program interfacing, and a third database for storing genomic variant characterizations received from the user application programs.
In practice, the invention involves a workflow where clinical records and genomic data are first collected and then processed to create structured data. This structured data is then stored in a central repository. User applications, such as those used by physicians or researchers, then access specific subsets of this data from a separate database that is optimized for their particular needs. This separation of data storage and access allows for more efficient application performance and greater flexibility in adapting the system to new data types or user requirements.
This approach differs from prior solutions that rely on a single, monolithic database structure. By using multiple databases, ’839 allows for purpose-specific optimization , which can improve data access speeds, simplify application development, and enable more rapid adaptation to changing needs. The patent addresses the problem of data silos and the difficulty of integrating diverse data types in a way that is both efficient and scalable.
In the late 2010s when '839 was filed, systems commonly relied on complex data analysis pipelines to process genomic information and clinical data. At a time when machine learning techniques were increasingly being adopted, hardware or software constraints made real-time analysis and integration of diverse data types non-trivial. The need for efficient data structuring and adaptable systems was paramount to handle the growing volume of medical data.
The examiner approved the application because they could not find existing prior art that taught all the features of the pending claims, either individually or in combination. Specifically, the examiner noted that while some references disclosed genomic sequencing, data storage, and application programs, they did not teach the specific three-database architecture, the use of a next-generation sequencer for both cancerous and normal cells, or the shaping of semi-structured data into structured data as claimed.
This patent contains 20 claims, with independent claims 1, 19, and 20. The independent claims are directed to a method, a system, and a non-transitory computer-readable storage medium for conducting genomic sequencing. The dependent claims generally elaborate on and refine the method of claim 1, adding details and features to the genomic sequencing process.
Definitions of key terms used in the patent claims.
US Latest litigation cases involving this patent.

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
Date
Description
Get instant alerts for new documents