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| OPPOSITION | - Shiraz Ali Shah, Roger A Garrett, "Distri bution of CRISPR spacer matches in viruses and plasmids of crenarchaeal acidothermophi les and implications fortheir inhibitory mechanism", Biochem Soc Trans, (20080101), vol. 37, no. 1, doi:10.1042/BST0370023, pages 23 - 28, XP055514485 |
| OPPOSITION | - MOEHLE E A, ET AL, "Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases + corrections", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20070201), vol. 104, no. 9, doi:10.1073/PNAS.0611478104, ISSN 0027-8424, pages 3055 - 3060, 6090, XP002518477 |
| OPPOSITION | - BEUMER KELLY J ET AL, "Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases.", PNAS, Proceedings of the National Academy of Sciences, National Academy of Sciences, US, US , (20081216), vol. 105, no. 50, doi:10.1073/pnas.0810475105, ISSN 1091-6490, pages 19821 - 19826, XP002782686 |
| OPPOSITION | - GORDLEY RUSSELL M ET AL, "Synthesis of programmable integrases", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20090301), vol. 106, no. 13, doi:10.1073/pnas.0812502106, ISSN 0027-8424, pages 5053 - 5058, XP002544501 |
| OPPOSITION | - Erika Brunet, Deniz Simsek, Mark Tomishima, Russell DeKelver, Vivian M. Choi, Philip Gregory, Fyodor Urnov, David M. Weinstock, and Maria Jasin, "Chromosomal translocations induced at specified loci in human stem cells", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20090630), vol. 106, no. 26, doi:10.1073/pnas.0902076106 , ISSN 0027-8424, pages 10620 - 10625, XP002722146 |
| OPPOSITION | - GROTH A C ET AL, "A phage integrase directs efficient site-specific integration in human cells.", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20000523), vol. 97, no. 11, doi:10.1073/pnas.090527097, ISSN 0027-8424, pages 5995 - 6000, XP002221880 |
| OPPOSITION | - Gasiunas G; Barrangou R; Horvath P; Siksnys V, "Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria", National Academy of Sciences, (20120000), vol. 109, no. 39, pages E2579 - E2586, XP055068588 |
| OPPOSITION | - G. Gasiunas, R. Barrangou, P. Horvath, V. Siksnys, "Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20120925), vol. 109, no. 39, doi:10.1073/pnas.1208507109, ISSN 0027-8424, pages E2579 - E2586, XP055068588 |
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| OPPOSITION | - PAPWORTH MONIKA, ET AL, "Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors.", Proceedings of the National Academy of Sciences, National Academy of Sciences, (20030218), vol. 100, no. 4, doi:10.1073/PNAS.242773399, ISSN 0027-8424, pages 1621 - 1626, XP002514674 |
| OPPOSITION | - SAUER B., HENDERSON N., "SITE-SPECIFIC DNA RECOMBINATION IN MAMMALIAN CELLS BY THE CRE RECOMBINASE OF BACTERIOPHAGE P1.", Proceedings of the National Academy of Sciences, National Academy of Sciences, (19880701), vol. 85., no. 14., doi:10.1073/pnas.85.14.5166, ISSN 0027-8424, pages 5166 - 5170., XP000615552 |
| OPPOSITION | - SCHIESTL R. H., ET AL., "INTEGRATION OF DNA FRAGMENTS BY ILLEGITIMATE RECOMBINATION IN SACCHAROMYCES CEREVISIAE.", Proceedings of the National Academy of Sciences, National Academy of Sciences, (19910901), vol. 88., doi:10.1073/pnas.88.17.7585, ISSN 0027-8424, pages 7585 - 7589., XP002920453 |
| OPPOSITION | - Bruno Tinland, Et Al, "The T-DNA-linked VirD2 protein contains two distinct functional nuclear localization signals", Proc. Natl. Acad. Sci., (19920801), vol. 89, doi:10.1073/pnas.89.16.7442, pages 7442 - 7446, XP055254906 |
| OPPOSITION | - KUSPA ET AL, "Tagging developmental genes in Dictyostelium by restriction enzyme mediated integration of plasmid DNA", Proceedings of the National Academy of Sciences, National Academy of Sciences, (19920901), vol. 89., doi:10.1073/pnas.89.18.8803, ISSN 0027-8424, pages 8803 - 8807., XP002115387 |
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| OPPOSITION | - REISS B. ET AL., "RecA protein stimulates homologous recombination in plants", Proceedings of the National Academy of Sciences, National Academy of Sciences, (19960402), vol. 93, no. 7, doi:10.1073/pnas.93.7.3094, ISSN 0027-8424, pages 3094 - 3098, XP002023622 |
| OPPOSITION | - BEERLI ROGER R ET AL, "Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks.", Proceedings of the National Academy of Sciences, National Academy of Sciences, (19981201), vol. 95, no. 25, doi:10.1073/pnas.95.25.14628, ISSN 0027-8424, pages 14628 - 14633, XP002187156 |
| OPPOSITION | - Feng Liang, Han Mingguang, Romanienko Peter J, Jasin Maria, Radding Charles M, "Homology-directed repair is a major double-strand break repair pathway in mammalian cells", Genetics and approved February, (19980401), vol. 95, no. 18, doi:10.1073/pnas.95.9.5172, pages 5172 - 5177, XP055502633 |
| OPPOSITION | - Daniele Derossi, Sophie Calvet, Alain Trembleau, Alié Brunissen, Gérard Chassaing and Alain Prochiantz, "Cell Internalization of the Third Helix of the Antennapedia Homeodomain Is Receptor-independent", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (19960726), vol. 271., no. 30., doi:10.1074/jbc.271.30.18188, ISSN 0021-9258, pages 18188 - 18193, XP002024485 |
| OPPOSITION | - EFTHYMIADIS A, BRIGGS L J, JANS D A, "The HIV-1 tat nuclear localization sequence confers novel nuclear import properties", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (19980116), vol. 273, no. 3, doi:10.1074/jbc.273.3.1623, ISSN 0021-9258, pages 1623 - 1628, XP003000854 |
| OPPOSITION | - Hamada Mitsuhiro, Sakulich Amy L., Koduru Shashi B., Maraia Richard J., "Transcription Termination by RNA Polymerase III in Fission Yeast", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20000310), vol. 275, no. 37, doi:10.1074/jbc.M003980200, ISSN 0021-9258, pages 29076 - 29081, XP093004140 |
| OPPOSITION | - Y.-S. Dai, Et Al, "The Transcription Factors GATA4 and dHAND Physically Interact to Synergistically Activate Cardiac Gene Expression through a p300-dependent Mechanism", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20020705), vol. 277, no. 27, doi:10.1074/jbc.M202490200, ISSN 0021-9258, pages 24390 - 24398, XP055251716 |
| OPPOSITION | - I.-H. Park, Et Al, "Regulation of Ribosomal S6 Kinase 2 by Mammalian Target of Rapamycin", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20020823), vol. 277, no. 35, doi:10.1074/jbc.M204080200, ISSN 0021-9258, pages 31423 - 31429, XP055251717 |
| OPPOSITION | - S. L. Planey, Et Al, "Inhibition of Glucocorticoid-induced Apoptosis in 697 Pre-B Lymphocytes by the Mineralocorticoid Receptor N-terminal Domain", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20021101), vol. 277, no. 44, doi:10.1074/jbc.M205085200, ISSN 0021-9258, pages 42188 - 42196, XP055251719 |
| OPPOSITION | - Braglia Priscilla, Percudani Riccardo, Dieci Giorgio, "Sequence Context Effects on Oligo(dT) Termination Signal Recognition by Saccharomyces cerevisiae RNA Polymerase III", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20050501), vol. 280, no. 20, doi:10.1074/jbc.M412238200, ISSN 0021-9258, pages 19551 - 19562, XP093004146 |
| OPPOSITION | - Alec E. Hodel, Michelle T. Harreman, Kanika F. Pulliam, Mary Elizabeth Harben, Jordan S. Holmes, Mary R. Hodel, Keith M. Berland, Anita H. Corbett, "Nuclear Localization Signal Receptor Affinity Correlates with in Vivo Localization in Saccharomyces cerevisiae", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20060818), vol. 281, no. 33, doi:10.1074/jbc.M601718200, ISSN 0021-9258, pages 23545 - 23556, XP055502581 |
| OPPOSITION | - Venkat Gopalan, Agustin Vioque, Sidney Altman, "RNase P: Variations and Uses", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US , (20020301), vol. 277, no. 9, doi:10.1074/jbc.R100067200, ISSN 0021-9258, pages 6759 - 6762, XP055647231 |
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| OPPOSITION | - HANDEL, E. et al., "Versatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors", Human Gene Ther., (20120000), vol. 23, doi:10.1089/hum.2011.140, pages 321 - 329, XP002730956 |
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| OPPOSITION | - SALOMON S, PUCHTA H, "Capture of genomic and T-DNA sequences during double-strand break repair in somatic plant cells", The EMBO journal / European Molecular Biology Organization, IRL Press, Oxford, Oxford , (19981015), vol. 17, no. 20, doi:10.1093/emboj/17.20.6086, ISSN 0261-4189, pages 6086 - 6095, XP002259898 |
| OPPOSITION | - Holger Puchta, "The repair of double-strand breaks in plants: mechanisms and consequences for genome evolution", JOURNAL OF EXPERIMENTAL BOTANY, OXFORD UNIVERSITY PRESS, GB, GB , (20041122), vol. 56, no. 409, doi:10.1093/jxb/eri025, ISSN 0022-0957, pages 1 - 14, XP002394840 |
| OPPOSITION | - LIEBER A., KIESSLING U., STRAUSS M., "High level gene expression in mammalian cells by a nuclear T7-phase RNA polymerase.", Nucleic Acids Research, Oxford University Press, GB, GB , (19890101), vol. 17., no. 21., doi:10.1093/nar/17.21.8485, ISSN 0305-1048, pages 8485 - 8493, XP002052543 |
| OPPOSITION | - S. J. Orlando, Santiago Y., Dekelver R. C., Freyvert Y., Boydston E. A., Moehle E. A., Choi V. M., Gopalan S. M., Lou J. F., Li J., Miller J. C., Holmes M. C., Gregory P. D., Urnov F. D., Cost G. J., "Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology", Nucleic Acids Research, Oxford University Press, GB, GB , (20100801), vol. 38, no. 15, doi:10.1093/nar/gkq512, ISSN 0305-1048, pages e152 - e152 - 15, XP055076783 |
| OPPOSITION | - Ting Li, Sheng Huang, Wen Zhi Jiang, David Wright, Martin H. Spalding, Donald P. Weeks and Bing Yang, "TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain", Nucleic Acids Research, Oxford University Press, GB, GB , (20110101), vol. 39, no. 1, doi:10.1093/NAR/GKQ704, ISSN 0305-1048, pages 359 - 372, XP002632807 |
| OPPOSITION | - Tomas Cermak, Erin L Doyle, Michelle Christian, Li Wang, Yong Zhang, Clarice Schmidt, Joshua A Baller, Nikunj V Somia, Adam J Bogdanove and Daniel F Voytas, "Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting.", Nucleic Acids research, Oxford University Press, GB, GB , (20110701), vol. 39, no. 12, doi:10.1093/nar/gkr218, ISSN 1362-4962, pages 1 - 11, XP002659530 |
| OPPOSITION | - C. L. Ramirez, M. T. Certo, C. Mussolino, M. J. Goodwin, T. J. Cradick, A. P. Mccaffrey, T. Cathomen, A. M. Scharenberg, J. K. Joung, "Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects", Nucleic Acids Research, Information Retrieval Ltd., (20120701), vol. 40, no. 12, doi:10.1093/nar/gks179, ISSN 03051048, pages 5560 - 5568, XP055065311 |
| OPPOSITION | - Sebastian Bultmann, Robert Morbitzer, Christine S. Schmidt, Katharina Thanisch, Fabio Spada, Janett Elsaesser, Thomas Lahaye, Heinrich Leonhardt, "Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers", Nucleic Acids Research, Oxford University Press, GB, GB , (20120701), vol. 40, no. 12, doi:10.1093/nar/gks199, ISSN 0305-1048, pages 5368 - 5377, XP055514381 |
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| OPPOSITION | - J. E. Dicarlo, J. E. Norville, P. Mali, X. Rios, J. Aach, G. M. Church, "Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems", Nucleic Acids Research, Information Retrieval Ltd., (20130401), vol. 41, no. 7, doi:10.1093/nar/gkt135, ISSN 03051048, pages 4336 - 4343, XP055086617 |
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| OPPOSITION | - H. J. Lee, J. Kweon, E. Kim, S. Kim, J.-S. Kim, "Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases", Genome Research, Cold Spring Harbor Laboratory Press, US, US , (20120301), vol. 22, no. 3, doi:10.1101/gr.129635.111, ISSN 1088-9051, pages 539 - 548, XP055243750 |
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| OPPOSITION | - M. Maresca, Lin V. G., Guo N., Yang Y., "Obligate Ligation-Gated Recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining", Genome Research, Cold Spring Harbor Laboratory Press, (20130301), vol. 23, no. 3, doi:10.1101/gr.145441.112, ISSN 10889051, pages 539 - 546, XP055077484 |
| OPPOSITION | - Y. H. Sung, J. M. Kim, H.-T. Kim, J. Lee, J. Jeon, Y. Jin, J.-H. Choi, Y. H. Ban, S.-J. Ha, C.-H. Kim, H.-W. Lee, J.-S. Kim, "Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases", Genome Research, Cold Spring Harbor Laboratory Press, US, US , (20140101), vol. 24, no. 1, doi:10.1101/gr.163394.113, ISSN 1088-9051, pages 125 - 131, XP055647267 |
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| OPPOSITION | - Ming Luo, C. W. Mark Pang, Alison E. Gerken, Thomas G. Brock, "Multiple Nuclear Localization Sequences Allow Modulation of 5-Lipoxygenase Nuclear Import", TRAFFIC, MUNKSGAARD,, DK, DK , (20040901), vol. 5, no. 11, doi:10.1111/j.1600-0854.2004.00227.x, ISSN 1398-9219, pages 847 - 854, XP055267733 |
| OPPOSITION | - P. Blancafort, "Designing Transcription Factor Architectures for Drug Discovery", Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, (20040101), vol. 66, no. 6, doi:10.1124/mol.104.002758, ISSN 0026895X, pages 1361 - 1371, XP055015595 |
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| OPPOSITION | - Lalith S Gunawardane, Saito Kuniaki, Nishida Kazumichi M, Miyoshi Keita, Kawamura Yoshinori, Nagami Tomoko, Siomi Haruhiko, Siomi Mikiko C, "A Slicer-Mediated Mechanism for Repeat-Associated siRNA 5Énd Formation in Drosophila", Science, (20070316), vol. 315, doi: 10.1126/science.1140494, pages 1587 - 1590, XP055646978 |
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| OPPOSITION | - JINEK, M. et al., "A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity", Science, (20120000), vol. 337, doi:10.1126/science.1225829, pages 816 - 821, XP055229606 |
| OPPOSITION | - M. Jinek, K. Chylinski, I. Fonfara, M. Hauer, J. A. Doudna, E. Charpentier, "A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity", Science, American Association for the Advancement of Science, (20120817), vol. 337, no. 6096, doi:10.1126/science.1225829, ISSN 00368075, pages 816 - 821, XP055067740 |
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| OPPOSITION | - J. S. Lee, A. G. Hadjipanayis, S. L. Welkos, "Venezuelan Equine Encephalitis Virus-Vectored Vaccines Protect Mice against Anthrax Spore Challenge", Infection and immunity, American Society for Microbiology, US, US , (20030301), vol. 71, no. 3, doi:10.1128/IAI.71.3.1491-1496.2003, ISSN 0019-9567, pages 1491 - 1496, XP055519514 |
| OPPOSITION | - Schouls Leo M., Reulen Sanne, Duim Birgitta, Wagenaar Jaap A., Willems Rob J. L., Dingle Kate E., Colles Frances M., Van Embden Jan D. A., "Comparative Genotyping of Campylobacter jejuni by Amplified Fragment Length Polymorphism, Multilocus Sequence Typing, and Short Repeat Sequencing: Strain Diversity, Host Range, and Recombination", Journal of clinical microbiology, American Society for Microbiology, US, US , (20030101), vol. 41, no. 1, doi:10.1128/JCM.41.1.15-26.2003, ISSN 0095-1137, pages 15 - 26, XP093004254 |
| OPPOSITION | - W. Tan, Dong Z., Wilkinson T. A., Barbas C. F., Chow S. A., "Human Immunodeficiency Virus Type 1 Incorporated with Fusion Proteins Consisting of Integrase and the Designed Polydactyl Zinc Finger Protein E2C Can Bias Integration of Viral DNA into a Predetermined Chromosomal Region in Human Cells", Journal of Virology, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, US , (20060215), vol. 80, no. 4, doi:10.1128/JVI.80.4.1939-1948.2006, ISSN 0022-538X, pages 1939 - 1948, XP055344657 |
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